Trpc6 (NM_001282087) Mouse Untagged Clone

CAT#: MC227535

Trpc6 (untagged) - Mouse transient receptor potential cation channel, subfamily C, member 6 (Trpc6), transcript variant 3

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Trpc6
• Synonyms: AV025995; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; TRP-6; Trrp6
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC227535 representing NM_001282087
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGCCAGAGCCCGAGGTTCGTGACCCGGAGGGGCGGCTCTCTAAAGGCTGCCCCTGGAGCCGGCACCC
  GGCGCAACGAGAGCCAGGACTATTTGCTGATGGACGAGCTGGGAGACGACGGCTACCCGCAGCTCCCGCT
  GCCACCGTATGGCTACTACCCCAGCTTCCGGGGTAATGAAAACAGACTGACTCACCGGCGGCAGACGATT
  CTTCGTGAGAAGGGAAGAAGGTTAGCTAATCGAGGACCAGCATACATGTTTAATGATCATTCAACAAGCC
  TGTCTATTGAGGAAGAACGCTTTCTAGATGCAGCTGAATATGGCAACATCCCAGTGGTGCGGAAGATGCT
  AGAAGAGTGTCATTCCCTCAATGTTAACTGTGTGGATTACATGGGCCAGAATGCCCTACAGCTGGCTGTG
  GCCAATGAGCACTTGGAAATCACAGAGCTGCTACTCAAGAAGGAAAACTTGTCTCGAGTTGGGGATGCTT
  TACTTTTAGCCATTAGTAAAGGTTATGTACGGATTGTGGAGGCAATCCTCAACCATCCAGCTTTTGCTGA
  AGGCAAAAGGTTAGCGACAAGCCCCAGCCAGTCTGAACTTCAGCAAGATGACTTTTATGCCTATGATGAA
  GATGGGACGCGGTTCTCCCATGATGTGACCCCAATCATTCTCGCTGCACATTGCCAGGAATATGAAATTG
  TGCATACCCTCCTGAGAAAGGGTGCCCGGATTGAGCGGCCTCATGATTACTTCTGCAAGTGTACAGAATG
  CAGCCAGAAGCAGAAGCATGATTCCTTCAGCCACTCTAGATCCAGGATCAATGCATACAAAGGTCTGGCA
  AGTCCAGCATACCTGTCATTGTCCAGTGAAGATCCAGTCATGACTGCTTTAGAACTTAGCAATGAGCTGG
  CAGTGCTTGCCAACATTGAGAAAGAGTTCAAGAATGACTACAGGAAGCTGTCTATGCAGTGCAAGGATTT
  CGTTGTTGGTCTCTTGGACCTCTGCAGAAACACAGAGGAAGTGGAGGCCATCCTGAATGGGGATGCAGAG
  ACTCGCCAGCCCGGGGACTTCGGCCGTCCAAATCTCAGCCGTTTAAAACTTGCTATTAAGTATGAAGTAA
  AAAAAGTAAGGCAGGGCGTGAGGCCCCTTTGTTACTTCAGTTTGTGTGTGTGGATATGCCAAGCTGGAAA
  GAGCAGGGGGTCATCCCGAGGAAGCATCTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282087
• ORF Size: 1221 bp
• Insert Size: 1221
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001282087.1, NP_001269016.1
• RefSeq Size: 3235
• RefSeq ORF: 1221
• Locus ID: 22068
• Gene Summary: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (3) lacks several exons and its 3'-terminal exon extends past a splice site that is used in variant 1. The encoded isoform (3) has a shorter and distinct C-terminus, compared to isoform 1.