Mknk1 (NM_001285488) Mouse Untagged Clone

CAT#: MC227577

Mknk1 (untagged) - Mouse MAP kinase-interacting serine/threonine kinase 1 (Mknk1), transcript variant 2

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Mknk1
• Synonyms: 2410048M24Rik; Mnk1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC227577 representing NM_001285488
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGCAGCAGTGAGCCCCTTCCCATCGTGGATTCTGACAAGAGGAGGAAGAAGAAGCGTAAGACCCGGG
  CCACCGACTCTCTGCCAGGAAAGTTTGAAGATGTGTACCAGCTGACCTCGGAATTGCTGGGAGAAGGAGC
  CTATGCCAAAGTCCAGGGTGCTGTGAACCTACAGAGTGGGAAGGAGTATGCTGTCAAAATCATCGAGAAG
  CAAGCCGGGCACAGTCGAAGTCGAGTGTTCCGTGAGGTGGAGACACTGTATCAGTGTCAAGGGAACAGGA
  ACATTTTGGAGCTGATTGAATTCTTTGAAGATGACACACGGTTTTACTTGGTCTTTGAGAAATTGCAAGG
  AGGCTCCATCCTAGCACACATCCAGAAGCGGAAGCACTTCAATGAGCGAGAAGCCAGTAGAGTGGTGCGG
  GACGTCGCCACTGCCCTTGACTTCCTGCACACTAAAGGCATTGCTCACCGTGATCTGAAGCCAGAAAACA
  TACTGTGTGAATCTCCAGAAAAGGTGTCTCCGGTGAAAATTTGTGACTTTGACTTGGGCAGTGGGGTAAA
  GTTGAACAACTCCTGCACTCCCATAACCACGCCAGAGCTGACTACTCCATGCGGCTCTGCAGAGTATATG
  GCACCTGAGGTGGTGGAGGTCTTTAGGGACGAGGCTACTTTCTATGACAAGCGCTGTGACCTGTGGAGCC
  TGGGTGTGGTCCTCTACATCATGCTGAGTGGCTACCCCCCCTTTGTAGGTCACTGTGGGGCTGACTGTGG
  CTGGGACCGGGGAGAGGTATGCAGGATGTGCCAGAACAAGCTGTTTGAGAGCATCCAGGAAGGCAAATAC
  GAGTTTCCTGACAAAGACTGGGCTCACATCTCCAACGAGGCCAAAGACCTCATCTCTAAGCTCCTGGTTC
  GAGATGCGAAGCAAAGACTCAGTGCTGCCCAGGTTCTGCAGCATCCATGGGTACAAGGGCAAGCTCCAGA
  AAGGGGACTCCCCACGCCGCAAGTCCTTCAGAGAAACAGCAGCACCATGGACTTGACTCTCTTCGCAGCT
  GAGGCCATTGCCCTGAACCGCCAGCTGTCTCAGCATGAGGAGAATGAACTGGCCGAGGAACAGGAGGCCC
  TAGCTGAGGGCCTCTGCTCCATGAAGCTGTCCCCTCCATCCAAATCTCGCCTGGCTCGAAGGCGAGCCCT
  GGCCCAGGCTGGCCGAAGCCGAGATGCAAACCCATGTTTGACACCGGCAGGGCTCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001285488
• ORF Size: 1248 bp
• Insert Size: 1248
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001285488.1, NP_001272417.1
• RefSeq Size: 2598
• RefSeq ORF: 1248
• Locus ID: 17346
• Gene Summary: This gene encodes a serine-threonine protein kinase that is activated by extracellular signal-regulated kinase or p38 mitogen-activated protein kinases, and it may function in cytokine and environmental stress responses. This kinase is required for phosphorylation of eukaryotic translation initiation factor 4E but it is not required for cell growth during development. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Oct 2013]
  Transcript Variant: This variant (2) lacks a portion of the 5' UTR and 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Both variants 2 and 3 encode isoform b. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.