Dnmt3l (NM_001284197) Mouse Untagged Clone

CAT#: MC227615

Dnmt3l (untagged) - Mouse DNA (cytosine-5-)-methyltransferase 3-like (Dnmt3l), transcript variant 3

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Dnmt3l
• Synonyms: D6Ertd14e; ecat7
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC227615 representing NM_001284197
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGTTCCCGGGAGACACCTTCTTCTTGCTCTAAGACCCTTGAAACCTTGGACCTGGAGACTTCCGACA
  GCTCTAGCCCTGATGCTGACAGTCCTCTGGAAGAGCAATGGCTGAAATCCTCCCCAGCCCTGAAGGAGGA
  CAGTGTGGATGTGGTACTGGAAGACTGCAAAGAGCCTCTGTCCCCCTCCTCGCCTCCGACAGGCAGAGAG
  ATGATCAGGTACGAAGTCAAAGTGAACCGACGGAGCATTGAAGACATCTGCCTCTGCTGTGGAACTCTCC
  AGGTGTACACTCGGCACCCCTTGTTTGAGGGAGGGTTATGTGCCCCATGTAAGGATAAGTTCCTGGAGTC
  CCTCTTCCTGTATGATGATGATGGACACCAGAGTTACTGCACCATCTGCTGTTCCGGGGGTACCCTGTTC
  ATCTGTGAGAGCCCCGACTGTACCAGATGCTACTGTTTCGAGTGTGTGGACATCCTGGTGGGCCCCGGGA
  CCTCAGAGAGGATCAATGCCATGGCCTGCTGGGTTTGCTTCCTGTGCCTGCCCTTCTCACGGAGTGGACT
  GCTGCAGAGGCGCAAGAGGTGGCGGCACCAGCTGAAGGCCTTCCATGATCAAGAGGGAGCGGGCCCTATG
  GAGATATACAAGACAGTGTCTGCATGGAAGAGACAGCCAGTGCGGGTACTGAGCCTTTTTAGAAATATTG
  ATAAAGTACTAAAGAGTTTGGGCTTTTTGGAAAGCGGTTCTGGTTCTGGGGGAGGAACGCTGAAGTACGT
  GGAAGATGTCACAAATGTCGTGAGGAGAGACGTGGAGAAATGGGGCCCCTTTGACCTGGTGTACGGCTCG
  ACGCAGCCCCTAGGCAGCTCTTGTGATCGCTGTCCCGGCTGGTACATGTTCCAGTTCCACCGGATCCTGC
  AGTATGCGCTGCCTCGCCAGGAGAGTCAGCGGCCCTTCTTCTGGATATTCATGGACAATCTGCTGCTGAC
  TGAGGATGACCAAGAGACAACTACCCGCTTCCTTCAGACAGAGGCTGTGACCCTCCAGGATGTCCGTGGC
  AGAGACTACCAGAATGCTATGCGGGTGTGGAGCAACATTCCAGGGCTGAAGAGCAAGCATGCGCCCCTGA
  CCCCAAAGGAAGAAGAGTATCTGCAAGCCCAAGTCAGAAGCAGGAGCAAGCTGGACGCCCCGAAAGTTGA
  CCTCCTGGTGAAGAACTGCCTTCTCCCGCTGAGAGAGTACTTCAAGTATTTTTCTCAAAACTCACTTCCT
  CTTTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001284197
• ORF Size: 1266 bp
• Insert Size: 1266
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001284197.1, NP_001271126.1
• RefSeq Size: 1672
• RefSeq ORF: 1266
• Locus ID: 54427
• Gene Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein that is a catalytically inactive regulatory factor of DNA methyltransferases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
  Transcript Variant: This variant (3) is expressed in testis, thymus, ovary, and heart, as well as in 7-day, 15-day, and 17-day embryo (PMID: 11306809). It differs in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same isoform 1.