Tfap2a (NM_001301674) Mouse Untagged Clone

CAT#: MC227696

Tfap2a (untagged) - Mouse transcription factor AP-2, alpha (Tfap2a), transcript variant 1b

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Tfap2a
• Synonyms: AP-2; Ap-2 (a); Ap2; AP2alpha; Ap2tf; Tcfap2a
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC227696 representing NM_001301674
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTTTGGAAACTGACGGATAATATCAAGTACGAAGACTGCGAGGACCGTCACGACGGCACCAGCAACG
  GGACGGCACGGTTGCCCCAGCTGGGCACTGTAGGTCAATCTCCCTACACCAGCGCCCCGCCGCTGTCCCA
  CACCCCTAATGCCGACTTCCAGCCTCCCTACTTCCCCCCGCCCTACCAGCCTATCTACCCCCAGTCGCAA
  GATCCTTACTCCCACGTCAACGACCCCTACAGCCTGAATCCTCTGCACGCCCAGCCGCAGCCGCAGCACC
  CGGGCTGGCCCGGTCAGAGGCAGAGCCAGGAATCTGGGCTCTTACACACACACCGGGGCTTACCCCACCA
  ACTGTCGGGCCTGGACCCTCGCAGGGACTATCGGCGGCACGAGGACCTCTTGCACGGCCCGCACGGGCTC
  GGCTCTGGGCTCGGGGACCTCCCGATCCACTCCTTACCTCACGCCATCGAGGACGTCCCGCACGTAGAAG
  ACCCGGGTATTAACATCCCAGATCAAACTGTAATTAAGAAAGGCCCCGTGTCCCTGTCCAAGTCCAACAG
  CAATGCTGTCTCCGCCATCCCTATTAACAAGGACAACCTCTTCGGTGGCGTGGTAAACCCCAACGAAGTC
  TTCTGTTCAGTTCCGGGTCGCCTGTCGCTCCTCAGCTCCACCTCGAAGTACAAGGTCACGGTGGCGGAAG
  TACAGCGGCGCCTCTCACCGCCCGAGTGTCTTAACGCGTCGCTCCTGGGCGGAGTACTGCGGAGAGCGAA
  GTCTAAGAATGGAGGGAGATCTTTAAGAGAAAAACTGGACAAGATAGGATTGAATCTGCCAGCAGGGAGA
  CGTAAAGCTGCCAACGTTACCCTCCTCACGTCACTAGTGGAAGGAGAAGCCGTCCACCTAGCCAGGGACT
  TTGGGTACGTGTGCGAAACTGAATTTCCTGCCAAAGCAGTAGCAGAATTTCTCAACCGACAACATTCCGA
  TCCCAATGAGCAAGTGGCAAGAAAAAACATGCTCCTGGCCACAAAACAGATCTGCAAAGAGTTCACTGAC
  CTGCTGGCTCAGGACCGATCTCCCCTGGGGAACTCGCGGCCCAATCCTATCCTGGAGCCTGGCATCCAGA
  GTTGCTTGACCCACTTCAACCTCATCTCCCATGGCTTCGGCAGCCCGGCGGTGTGTGCAGCGGTTACGGC
  CCTGCAGAACTATCTCACCGAGGCCCTCAAGGCCATGGACAAAATGTACCTCAGCAACAACCCCAACAGC
  CACACGGACAACAGCGCCAAAAGCAGTGACAAAGAAGAGAAACACAGAAAGTGA
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-RsrII
• ACCN: NM_001301674
• ORF Size: 1314 bp
• Insert Size: 1314
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001301674.1, NP_001288603.1
• RefSeq Size: 3479
• RefSeq ORF: 1314
• Locus ID: 21418
• Gene Summary: This gene is a member of the activator protein 2 (AP-2) transcription factor family. The protein encoded by this gene can act as both an activator and repressor of gene transcription, and plays an important role in early embryogenesis, specifically in cranial development. This protein forms both homodimers and heterodimers, and binds to a GC-rich consensus sequence found in some promoters and enhancers. Disruption of this gene causes perinatal death, with neural tube, craniofacial, and limb mesenchyme defects. Alternative splicing results in multiple transcript variants that encode multiple protein isoforms. [provided by RefSeq, Sep 2014]
  Transcript Variant: This variant (1b) differs in the 5' UTR compared to variant 1a. Both variants 1a and 1b encode the same isoform (1).