Mpl (NM_001285497) Mouse Untagged Clone

CAT#: MC227838

Mpl (untagged) - Mouse myeloproliferative leukemia virus oncogene (Mpl), transcript variant 4

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Mpl
• Synonyms: c-mpl; CD110; hlb219; TPO-R
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC227838 representing NM_001285497
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCCTCTTGGGCCCTCTTCATGGTCACCTCCTGCCTCCTCTTGGCCCTTCCAAACCAGGCACAAGTCA
  CCAGCCAAGATGTCTTCTTGCTGGCCTTGGGCACAGAGCCCCTGAACTGCTTCTCCCAAACATTTGAGGA
  CCTCACCTGCTTCTGGGATGAGGAAGAGGCAGCACCCAGTGGGACATACCAGCTGCTGTATGCCTACCGA
  GGAGAGAAGCCCCGTGCATGCCCCCTGTATTCCCAGAGTGTGCCCACCTTTGGAACCCGGTATGTGTGCC
  AGTTTCCAGCCCAGGATGAAGTGCGCCTCTTCTTTCCGCTGCACCTCTGGGTGAAGAATGTGTCCCTCAA
  CCAGACTTTGATCCAGCGGGTGCTGTTTGTGGATAGTGTGGGCCTGCCAGCTCCCCCCAGGGTCATCAAG
  GCCAGGGGTGGGAGCCAACCAGGGGAACTTCAGATCCACTGGGAGGCCCCTGCTCCTGAAATCAGTGACT
  TCCTGAGGCATGAACTCCGCTATGGCCCCACGGACTCCAGCAACGCCACTGCCCCCTCCGTCATTCAGCT
  GCTCTCCACAGAAACCTGCTGCCCCACTTTGTGGATGCCGAACCCAGTCCCTGTTCTTGACCAGCCTCCG
  TGTGTTCATCCGACAGCATCCCAACCGCATGGACCAGTGAGGACCTCCCCAGCTGGAGAAGCTCCATTTC
  TGACAGTGAAGGGTGGAAGCTGTCTCGTCTCAGGCCTCCAGGCTGGCAAATCCTACTGGCTCCAGCTACG
  CAGCCAACCCGACGGGGTCTCCCTTCGTGGCTCCTGGGGACCCTGGTCCTTCCCTGTGACTGTGGATCTT
  CCAGGAGATGCAGTGACAATTGGACTTCAGTGCTTTACCTTGGATCTGAAGATGGTCACCTGCCAGTGGC
  AGCAACAAGACCGCACTAGCTCCCAAGGCTTCTTCCGCCACAGCAGGACGAGGTGCTGCCCCACAGACAG
  GGACCCCACCTGGGAGAAATGTGAAGAGGAGGAACCGCGTCCAGGATCACAGCCCGCTCTCGTCTCCCGC
  TGCCACTTCAAGTCACGAAATGACAGTGTTATTCACATCCTTGTAGAGGTGACCACAGCGCAAGGTGCCG
  TTCACAGCTACCTGGGCTCCCCTTTTTGGATCCACCAGGCTGTGCTCCTTCCCACCCCGAGCCTGCACTG
  GAGGGAGGTCTCAAGTGGAAGGCTGGAGTTGGAGTGGCAGCACCAGTCATCTTGGGCAGCTCAAGAGACC
  TGCTACCAGCTCCGGTACACGGGAGAAGGCCGTGAGGACTGGAAGGAGACTGAGGCATGCTTTGTGGCCC
  TCGCTTCCAGACCTACACCGGGTCCTAGGCCAGTACCTCAGAGACACTGCAGCCCTAAGTCCTTCTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001285497
• ORF Size: 1398 bp
• Insert Size: 1398
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001285497.1, NP_001272426.1
• RefSeq Size: 2701
• RefSeq ORF: 1398
• Locus ID: 17480
• Gene Summary: Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (4) lacks two alternate exons, which results in a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (4) has a distinct C-terminus and is shorter than isoform 1.