Mpl (NM_001285497) Mouse Tagged ORF Clone

CAT#: MR230049

Mpl (myc-DDK-tagged) - Mouse myeloproliferative leukemia virus oncogene (Mpl), transcript variant 4

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Mpl
• Synonyms: c-mpl; CD110; hlb219; TPO-R
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR230049 representing NM_001285497
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCCTCTTGGGCCCTCTTCATGGTCACCTCCTGCCTCCTCTTGGCCCTTCCAAACCAGGCACAAGTCA
  CCAGCCAAGATGTCTTCTTGCTGGCCTTGGGCACAGAGCCCCTGAACTGCTTCTCCCAAACATTTGAGGA
  CCTCACCTGCTTCTGGGATGAGGAAGAGGCAGCACCCAGTGGGACATACCAGCTGCTGTATGCCTACCGA
  GGAGAGAAGCCCCGTGCATGCCCCCTGTATTCCCAGAGTGTGCCCACCTTTGGAACCCGGTATGTGTGCC
  AGTTTCCAGCCCAGGATGAAGTGCGCCTCTTCTTTCCGCTGCACCTCTGGGTGAAGAATGTGTCCCTCAA
  CCAGACTTTGATCCAGCGGGTGCTGTTTGTGGATAGTGTGGGCCTGCCAGCTCCCCCCAGGGTCATCAAG
  GCCAGGGGTGGGAGCCAACCAGGGGAACTTCAGATCCACTGGGAGGCCCCTGCTCCTGAAATCAGTGACT
  TCCTGAGGCATGAACTCCGCTATGGCCCCACGGACTCCAGCAACGCCACTGCCCCCTCCGTCATTCAGCT
  GCTCTCCACAGAAACCTGCTGCCCCACTTTGTGGATGCCGAACCCAGTCCCTGTTCTTGACCAGCCTCCG
  TGTGTTCATCCGACAGCATCCCAACCGCATGGACCAGTGAGGACCTCCCCAGCTGGAGAAGCTCCATTTC
  TGACAGTGAAGGGTGGAAGCTGTCTCGTCTCAGGCCTCCAGGCTGGCAAATCCTACTGGCTCCAGCTACG
  CAGCCAACCCGACGGGGTCTCCCTTCGTGGCTCCTGGGGACCCTGGTCCTTCCCTGTGACTGTGGATCTT
  CCAGGAGATGCAGTGACAATTGGACTTCAGTGCTTTACCTTGGATCTGAAGATGGTCACCTGCCAGTGGC
  AGCAACAAGACCGCACTAGCTCCCAAGGCTTCTTCCGCCACAGCAGGACGAGGTGCTGCCCCACAGACAG
  GGACCCCACCTGGGAGAAATGTGAAGAGGAGGAACCGCGTCCAGGATCACAGCCCGCTCTCGTCTCCCGC
  TGCCACTTCAAGTCACGAAATGACAGTGTTATTCACATCCTTGTAGAGGTGACCACAGCGCAAGGTGCCG
  TTCACAGCTACCTGGGCTCCCCTTTTTGGATCCACCAGGCTGTGCTCCTTCCCACCCCGAGCCTGCACTG
  GAGGGAGGTCTCAAGTGGAAGGCTGGAGTTGGAGTGGCAGCACCAGTCATCTTGGGCAGCTCAAGAGACC
  TGCTACCAGCTCCGGTACACGGGAGAAGGCCGTGAGGACTGGAAGGAGACTGAGGCATGCTTTGTGGCCC
  TCGCTTCCAGACCTACACCGGGTCCTAGGCCAGTACCTCAGAGACACTGCAGCCCTAAGTCCTTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR230049 representing NM_001285497
  Red=Cloning site Green=Tags(s)
  
  MPSWALFMVTSCLLLALPNQAQVTSQDVFLLALGTEPLNCFSQTFEDLTCFWDEEEAAPSGTYQLLYAYR
  GEKPRACPLYSQSVPTFGTRYVCQFPAQDEVRLFFPLHLWVKNVSLNQTLIQRVLFVDSVGLPAPPRVIK
  ARGGSQPGELQIHWEAPAPEISDFLRHELRYGPTDSSNATAPSVIQLLSTETCCPTLWMPNPVPVLDQPP
  CVHPTASQPHGPVRTSPAGEAPFLTVKGGSCLVSGLQAGKSYWLQLRSQPDGVSLRGSWGPWSFPVTVDL
  PGDAVTIGLQCFTLDLKMVTCQWQQQDRTSSQGFFRHSRTRCCPTDRDPTWEKCEEEEPRPGSQPALVSR
  CHFKSRNDSVIHILVEVTTAQGAVHSYLGSPFWIHQAVLLPTPSLHWREVSSGRLELEWQHQSSWAAQET
  CYQLRYTGEGREDWKETEACFVALASRPTPGPRPVPQRHCSPKSF
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001285497
• ORF Size: 1395 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001285497.1, NP_001272426.1
• RefSeq Size: 2701
• RefSeq ORF: 1398
• Locus ID: 17480
• MW: 52.4 kDa
• Gene Summary: Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses. [UniProtKB/Swiss-Prot Function]