Mst1r (NM_001287261) Mouse Untagged Clone

CAT#: MC227896

Mst1r (untagged) - Mouse macrophage stimulating 1 receptor (c-met-related tyrosine kinase) (Mst1r), transcript variant 2

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Mst1r
• Synonyms: CD136; CDw136; Fv-2; Fv2; PTK8; Ron; STK
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC227896 representing NM_001287261
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACCGTGGGTGGTGAGGTCTGCCAACATGAGCTCCGGGGGGATGTGGTGATCTGCCCCCTGCCCCCTT
  CCCTGCAACTTGGCAAGGATGGTGTCCCATTGCAGGTCTGTGTAGACGGTGGGTGTCACATCCTGAGCCA
  AGTGGTTCGCTCAAGCCCAGGCAGGGCCTCACAGAGGATACTCCTTATTGCTCTTCTGGTCTTGATCCTG
  CTTGTGGCTGTGCTGGCCGTTGCCCTGATCTTTAACTCCCGAAGACGGAAAAAGCAGCTAGGTGCTCACT
  CCCTCTCCCCAACAACACTCTCTGACATCAACGATACAGCTTCCGGGGCTCCGAACCATGAAGAATCGTC
  AGAGAGTAGGGATGGGACAAGTGTCCCACTGCTGCGGACAGAGTCTATCCGGCTCCAGGATCTGGACAGG
  ATGCTCCTAGCTGAGGTCAAGGATGTACTGATTCCCCATGAACAAGTGGTCATCCATACTGACCAAGTCA
  TTGGCAAAGGCCACTTTGGTGTTGTCTACCACGGAGAATATACAGACGGAGCACAGAATCAGACCCACTG
  TGCCATCAAGTCTCTGAGTCGCATTACAGAGGTGCAGGAGGTGGAGGCTTTCCTGCGGGAGGGGCTGCTC
  ATGCGTGGCCTACATCACCCAAACATCCTGGCTCTCATCGGTATCATGCTGCCCCCGGAGGGGCTTCCCC
  GGGTGCTGTTGCCCTATATGCGCCACGGAGACCTGCTTCATTTCATTCGCTCCCCTCAGAGGAACCCCAC
  TGTGAAGGATCTTGTCAGCTTTGGCCTGCAGGTAGCCTGTGGTATGGAGTACCTGGCAGAGCAGAAGTTC
  GTGCACAGAGACCTGGCTGCTAGGAACTGCATGCTGGACGAGTCATTCACAGTCAAGGTGGCTGACTTTG
  GTCTGGCACGGGGCGTCCTAGACAAGGAATACTACAGTGTTCGCCAGCATCGCCATGCTCGCCTGCCAGT
  CAAATGGATGGCACTGGAGAGCCTGCAGACCTACAGGTTCACCACCAAGTCCGATGTGTGGTCATTCGGG
  GTGCTGCTCTGGGAGCTACTAACACGGGGTGCTCCACCCTACCCCCATATCGATCCCTTCGACCTCTCTC
  ACTTCCTGGCTCAGGGCCGTCGCCTGCCTCAGCCTGAGTACTGTCCTGATTCACTGTATCACGTGATGCT
  TCGATGCTGGGAGGCTGACCCAGCGGCACGACCCACCTTCAGAGCCCTAGTGCTGGAAGTAAAGCAGGTA
  GTGGCCTCACTGCTTGGGGACCACTATGTGCAGCTGACAGCAGCTTATGTGAACGTAGGCCCCAGAGCGG
  TGGATGATGGGAGTGTGCCTCCGGAGCAGGTACAGCCCTCGCCTCAGCATTGCAGGAGCACGTCAAAGCC
  CCGGCCTCTCTCAGAGCCACCCCTGCCCACTTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001287261
• ORF Size: 1434 bp
• Insert Size: 1434
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001287261.1, NP_001274190.1
• RefSeq Size: 1796
• RefSeq ORF: 1434
• Locus ID: 19882
• Gene Summary: This gene encodes a precursor protein that is proteolytically cleaved to yield an alpha chain and a beta chain which form a membrane-spanning heterodimer. The encoded protein belongs to a family of cell-surface receptor tyrosine kinases involved in signaling from the cell surface to the intracellular environment. The binding of the encoded protein to its ligand, macrophage-stimulating protein, mediates several biological activities including wound healing, tumor immunity, macrophage activation and hematopoiesis as well as cell growth, motility, survival and adhesion. The protein encoded by this gene also functions in early development and the macrophage-mediated inflammatory response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013].
  Transcript Variant: This variant (2) represents the use of an alternate promoter, differs in the 5' UTR, lacks a significant portion of the 5' coding region and initiates translation at a downstream start codon compared to variant 1. The encoded isoform (2, also known as short-form Ron or SF-Ron or sf-Stk) has a shorter N-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.