Xiap (NM_001301641) Mouse Untagged Clone

CAT#: MC228030

Xiap (untagged) - Mouse X-linked inhibitor of apoptosis (Xiap), transcript variant 2

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Xiap
• Synonyms: 1110015C02Rik; Aipa; Api3; Birc4; IAP3; ILP-1; MIHA
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC228030 representing NM_001301641
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACTTTTAACAGTTTTGAAGGAACTAGAACTTTTGTACTTGCAGACACCAATAAGGATGAAGAATTTG
  TAGAAGAGTTTAATAGATTAAAAACATTTGCTAACTTCCCAAGTAGTAGTCCTGTTTCAGCATCAACATT
  GGCGCGAGCTGGGTTTCTTTATACCGGTGAAGGAGACACCGTGCAATGTTTCAGTTGTCATGCGGCAATA
  GATAGATGGCAGTATGGAGACTCAGCTGTTGGAAGACACAGGAGAATATCCCCAAATTGCAGATTTATCA
  ATGGTTTTTATTTTGAAAATGGTGCTGCACAGTCTACAAATCCTGGTATCCAAAATGGCCAGTACAAATC
  TGAAAACTGTGTGGGAAATAGAAATCCTTTTGCCCCTGACAGGCCACCTGAGACTCATGCTGATTATCTC
  TTGAGAACTGGACAGGTTGTAGATATTTCAGACACCATATACCCGAGGAACCCTGCCATGTGTAGTGAAG
  AAGCCAGATTGAAGTCATTTCAGAACTGGCCGGACTATGCTCATTTAACCCCCAGAGAGTTAGCTAGTGC
  TGGCCTCTACTACACAGGGGCTGATGATCAAGTGCAATGCTTTTGTTGTGGGGGAAAACTGAAAAATTGG
  GAACCCTGTGATCGTGCCTGGTCAGAACACAGGAGACACTTTCCCAATTGCTTTTTTGTTTTGGGCCGGA
  ACGTTAATGTTCGAAGTGAATCTGGTGTGAGTTCTGATAGGAATTTCCCAAATTCAACAAACTCTCCAAG
  AAATCCAGCCATGGCAGAATATGAAGCACGGATCGTTACTTTTGGAACATGGACATCCTCAGTTAACAAG
  GAGCAGCTTGCAAGAGCTGGATTTTATGCTTTAGGTGAAGGCGATAAAGTGAAGTGCTTTCACTGTGGAG
  GAGGGCTCACGGATTGGAAGCCAAGTGAAGACCCTTGGGAACAGCATGCGAAGTGGTACCCAGGGTGCAA
  ATACCTATTGGATGAGAAGGGGCAAGAATATATAAATAATATTCATTTAACCCATTCACTTGAGGAATCT
  TTGGGAAGAACTGCTGAAAAAACACCATCGCTAACTAAAAAAATCGATGATACCATCTTCCAGAATCCTA
  TGGTGCAAGAAGCTATACGAATGGGATTTAGCTTCAAGGACATTAAGAAAACAATGGAAGAAAAAATCCA
  AACATCCGGGAGCAGCTATCTATCACTTGAGGTCCTGATTGCAGATCTTGTGAGTGCTCAGAAAGATAAT
  ACGGAGGATGAGTCAAGTCAAACTTCATTGCAGAAAGACATTAGTACTGAAGAGCAGCTAAGGCGCCTAC
  AAGAGGAGAAGCTTTGCAAAATCTGTATGGATAGAAATATTGCTATCGTTTTTGTTCCTTGTGGACATCT
  GGTCACTTGTAAACAGTGTGCAGAAGCAGTTGACAAATGTCCCATGTGCTACACCGTCATTACGTTCAAG
  CAAAAAATTTTTATGTCTTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001301641
• ORF Size: 1491 bp
• Insert Size: 1491
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001301641.1, NP_001288570.1
• RefSeq Size: 6481
• RefSeq ORF: 1491
• Locus ID: 11798
• Gene Summary: The protein encoded by this gene is a member of the inhibitor of apoptosis (IAP) family of proteins. While first identified for its role in blocking apoptosis, this protein modulates many other signaling processes including nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) pathways and inflammatory responses. This protein blocks apoptosis by binding and inhibiting target caspases after they have been activated. Binding occurs to some, but not all, caspases. This protein has several conserved regions, including baculoviral IAP repeat (BIR) motifs and a RING finger E3 ligase domain. In humans, mutations in this gene are linked to immunodeficiency in X-linked lymphoproliferative syndrome type-2 (XLP-2). A pseudogene of this gene is found on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.