Fzd5 (NM_001042659) Mouse Untagged Clone

CAT#: MC228382

Fzd5 (untagged) - Mouse frizzled homolog 5 (Drosophila) (Fzd5), transcript variant 2

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Fzd5
• Synonyms: 5330434N09Rik; AI427138; Fz-5; Fz5; mFz5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC228382 representing NM_001042659
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCTCGACCCGACCCGTCTGCGCCTCCCTCTCTTCTGCTGCTGTTGCTGGCGCAGCTGGTGGGCCGGG
  CAGCGGCCGCCTCCAAGGCCCCGGTGTGCCAGGAAATCACGGTGCCCATGTGCCGAGGCATCGGCTACAA
  CCTGACGCACATGCCCAACCAGTTCAACCATGACACGCAGGACGAAGCAGGCCTGGAGGTGCACCAATTC
  TGGCCGCTTGTGGAGATCCACTGCTCACCGGACCTGCGCTTCTTCCTGTGCTCTATGTACACGCCCATCT
  GTTTGCCTGACTACCACAAGCCGCTACCACCGTGCCGTTCCGTGTGCGAGCGCGCCAAGGCCGGCTGCTC
  GCCGCTCATGCGCCAGTACGGCTTCGCCTGGCCCGAGCGCATGAGCTGCGACCGCCTCCCTGTGCTGGGC
  GGCGACGCCGAGGTTCTGTGTATGGATTATAACCGAAGCGAAGCCACCACCGCGTCCCCTAAGTCCTTCC
  CGGCCAAACCTACACTCCCAGGACCACCAGGGGCGCCATCTTCCGGGGGCGAGTGCCCCTCGGGAGGCCC
  ATCCGTGTGCACGTGCCGCGAGCCCTTCGTGCCCATCCTGAAGGAGTCACACCCACTCTACAACAAGGTG
  CGCACCGGCCAAGTGCCCAACTGCGCGGTGCCCTGCTACCAGCCGTCCTTCAGCCCGGACGAGCGCACAT
  TCGCCACCTTCTGGATTGGCCTGTGGTCTGTGCTGTGCTTCATCTCCACGTCCACCACCGTTGCCACCTT
  CCTCATTGACATGGAACGATTCCGCTACCCTGAGCGCCCCATCATCTTCTTGTCTGCGTGCTACCTGTGT
  GTGTCACTGGGATTCTTGGTGCGCCTGGTAGTGGGCCATGCCAGCGTCGCTTGCAGCCGTGAGCACAGCC
  ACATTCACTATGAGACTACCGGCCCTGCGCTGTGCACGGTTGTCTTCCTCTTAGTCTATTTCTTTGGCAT
  GGCCAGCTCCATCTGGTGGGTCATCCTGTCGCTCACCTGGTTCTTGGCGGCTGGCATGAAGTGGGGCAAT
  GAAGCCATCGCAGGTTATGCACAGTACTTCCACCTTGCTGCCTGGCTCATCCCCAGTGTCAAGTCCATTA
  CGGCGCTGGCACTGAGCTCGGTGGACGGGGACCCAGTGGCTGGCATCTGCTATGTGGGCAACCAAAACCT
  GAACTCACTACGAGGCTTTGTCTTGGGCCCACTGGTGCTGTACCTGTTGGTGGGCACGCTCTTCCTTCTG
  GCAGGCTTCGTGTCACTCTTCCGCATCCGGAGCGTCATCAAGCAGGGTGGCACTAAGACGGACAAGCTAG
  AGAAGCTCATGATCCGCATCGGCATCTTCACCCTGCTCTACACGGTGCCAGCCAGCATCGTGGTGGCCTG
  CTACCTGTATGAGCAGCACTACCGGGAGAGCTGGGAGGCAGCCCTCACCTGCGCGTGTCCGGGACCGGAC
  GCTGGCCAGCCACGCGCCAAACCCGAGTACTGGGTGCTCATGCTCAAGTACTTCATGTGCCTGGTGGTGG
  GCATCACGTCGGGAGTCTGGATCTGGTCCGGCAAGACTCTGGAGTCTTGGCGGCGGTTCACCAGCCGCTG
  CTGCTGCAGCTCTCGGCGGGGCCACAAGAGCGGTGGCGCTATGGCCGCAGGAGACTATGCGGAGGCCAGC
  GCCGCGCTCACCGGCAGGACCGGGCCGCCTGGCCCCACCGCCGCATACCACAAGCAAGTGTCCCTGTCGC
  ACGTATAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001042659
• ORF Size: 1758 bp
• Insert Size: 1758
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001042659.1, NP_001036124.1
• RefSeq Size: 6823
• RefSeq ORF: 1758
• Locus ID: 14367
• Gene Summary: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Plays a role in yolk sac angiogenesis and in placental vascularization. Binds to Wnt2, Wnt10B, Wnt5A, but not to Wnt2B or Wnt4. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.