Dsc3 (NM_001291809) Mouse Untagged Clone

CAT#: MC229028

Dsc3 (untagged) - Mouse desmocollin 3 (Dsc3), transcript variant 2

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Dsc3
• Synonyms: 5430426I24Rik
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC229028 representing NM_001291809
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGTGGTTCCTGAGTTCCGGAGCCCACAGTGCAGGGCACTATGCACGAAGCTGCTGCTGACCCTCTGGG
  TCTTCAGTTTTGTTGGTGAAGCCTGTAAAAAGGTGACATTTCATGTACCTTCAACACTAGAGGCAGACAA
  GATCATCGGAAGAGTTAGTTTGAAAGAGTGTCTCAGCTCGGCAGATGGCATCATGCCAAGTGATCCTGAT
  TTCAGAGTTCTAGATGATGGGTCAGTTTATCCGACCAGAGCTGTTGTATTGTCTGATGAGAAAAGATCTT
  TTACCATTCAGCTTTCTGATTCAAAGATGCAGACACAGAAAGAGATCCCTGTAATCCTGGAGCACAAGAA
  GAAGGTACTGAAGAAAAGACACACTAAGGAAACTGTCCTCAGAAGATCTAAGAGAAGATGGGCACCCATT
  CCATGTTCAATGCAAGAAAATTCCTTGGGTCCCTTCCCATTGTTTCTTCAACAGGTTCAGTCTGATGCAG
  CTCAGAACTACACAGTCTTCTATTCAATAAGTGGGCGTGGAGCTGATCAAGAACCACTTAACTGGTTTTT
  CATCGAGAGAGACACTGGGAATCTATATTGTACTCGGCCTGTGGATCGTGAGGAATATGATGTTTTTGAT
  TTGATTGCCTATGCATCCACTGCAGATGGCTATTCAGCAGATTTACCTCTCCCACTGCCCATCAAAATAG
  AGGATGAAAATGACAATTACCCTCTTTTTACAGAAGCAATTTATGCTTTTGAAGTTCCAGAAGGCAGTAG
  ACTTGGTACTGTAGTGGGAACAGTTTGTGCCACGGATAAAGATGAGCCTGACACTATGCACACACGCCTC
  AAGTACAGCATCTTGGAGCAGACCCCACCATCACCTGGGCTTTTTTCTGTGCACCCTGACACAGGTGTCA
  TCACCACCGTCTCTCACTACATGGACAGAGAGGTCGTGGACAAGTACAAACTGATAATGAAAGTTCAGGA
  CATGAATGGCCAATTTTTTGGACTAATCAGTACATCAACTTGTATCATAACTGTGCAAGATTCCAATGAC
  AATGCACCCACATTCAGACAAAATACTTATGAAACTGCTGTGGAGGAAAATACATATAATGTTGAAATCT
  TGCGCATACCTGTAGATGATAAGGACATGATTAACACTGCCAACTGGAAGGCAAATTTCACCATCTTAAA
  AGGAAATGAAAATGGATGGTTCAAAATCACAACAGACCCAGTGACAAATGAAGGTGTTCTGTGTGTTGTG
  AAGCCACTGGATTATGAAGAAAATCGTCAAGTGACCCTAGAGATTGGTGTGAACAACGAAGCTCCATTCA
  TTAAAGATGTTGCAAACCGAATTCCCACCATGAACCGGGCTATGGTTACAGTACATGTGAAGGATCAGAA
  TGAGGGGCCAGAATGCAAGCCCCCAGAGCAATATGTGCGGATCAAAGAGAACTCAGCAGTTGGGTCTAAG
  ATCAATGGCTACAAGGCCTACGACCCTGAAACCAAGAATAGCAATGGCTTAAGGTACAAAAAATTGCAGG
  ATCCTAAAGACTGGGTCAGCATTGAAGAAGTTTCGGGGTTGCTTACCATATCAAAAACCCTAGACAGAGA
  AATAATGGCTCCAAGAAATGACATGTACAATATTACAGTCATGGCAATTGACCAAGAGGGTAAATCATGC
  ACAGGAACACTTGCAGTGAACATCGAGGATGTGAATGACAACGCACCAGAGATAATTCAAGATTATATTG
  TTATCTGTAAGCCAAAGATGGGGTACACGGACATTTCAGCTGTGGATCCTGATGAACCTATCCATGGCCC
  TCCCTTTCAGTTCAACTTGGCAAACACTTCTCCAGAAGTCAACAGAATCTGGACCCTCAACCAAGTTAAT
  GATACAGCTGCTCGCCTGTCCTATCAGAAAACTGCGGATGTTCAAATATACAACGTTCCTGTTACTGTAA
  AAGACAGAGCAGGCCAATCTGCAACCAAAATCTTGAGAGTTAACCTGTGTGATTGTACTCATCCCAGCCA
  ATGTCCGCTCAGATCAAGGAGTGCAGGAATTACCCTGGGAAAGTGGGCCATCCTTGCCATCTTGCTGGGC
  ATTGCTCTGCTATTTTCGGTACTGCTAACTTTGGTATGTGGAGTTGTTACTGCCCGAAAAGGAAAACACT
  TCCCTGAAGATTTAGCGCAGCAAAACTTAATTATATCAAATACCGAAGCACCTGGGGATGACAGAGTGTG
  CTCTGCCAATGGATTCACCACCCACACTGCCAACAACTCCAGCCAAGGCTTCTGTGGTACAATGGGGTCA
  GGAATGAGGAATGGTGGGCAGGAGACCATCGAGATGATGAAAGGACACCAGACCTTGGACTCCTGCCGTG
  TGGCCGGGCATCACCATACCCTGGACTCCGGCAGGGGAGGACACATGGATACTGACAACTGCAGATACAC
  ATACTCAGAGTGGCACAGTTTCACTCAACCCCGACTTGGTGAAGACTCCATTAGAGGACACACTGGTTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001291809
• ORF Size: 2520 bp
• Insert Size: 2520
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001291809.1, NP_001278738.1
• RefSeq Size: 5348
• RefSeq ORF: 2520
• Locus ID: 13507
• Gene Summary: This gene encodes a member of the cadherin family of proteins that mediates adhesion in desmosomes. Together with desmogleins, the encoded protein forms the transmembrane core of desmosomes, a multiprotein complex involved in cell adhesion, organization of the cytoskeleton, cell sorting and cell signaling. Mice lacking the encoded protein exhibit a pre-implantation lethal phenotype. This gene is located in a cluster of desmosomal cadherin genes on chromosome 18. This gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature protein. [provided by RefSeq, Jul 2016]
  Transcript Variant: This variant (2) contains an alternate exon in the 3' end compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. This isoform (2) may undergo proteolytic processing similar to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.