Fgd4 (NM_001301817) Mouse Untagged Clone

CAT#: MC229108

Fgd4 (untagged) - Mouse FYVE, RhoGEF and PH domain containing 4 (Fgd4), transcript variant 1

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Fgd4
• Synonyms: 9030023J02Rik; 9330209B17Rik; Frabp; ZFYVE6
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC229108 representing NM_001301817
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAACAGCGAGAGCGACCATAACTTCAGGCGGGTGGCCATCCGGCGGAAGTCAGGCTCCTACCTGCCGC
  CCGGGATCCCCCGGCCCTGGAGCAGGCCTTCGCCGCAATTGCGGCGCCTTGACCGTGTCGCGCAACCCAG
  CCAGGCCGCAGGCATCAATACTTGTGCAAAGGTTACTCCACCTTGTACGACAAGCAACACAACCACAGAA
  GCTCAGGGAATAAATGGGAGGACACCAGCAAAACGCTCCACTGCAAGTGCAAAGCCACAAGTGCCTCCAA
  AACCATTATATCTGCAGAATTCACCTTCATCCCATATTCCCCAAGTCCCCAGGCATAAAGCTTTACCTAG
  TGCAAAGCCAAGGATGGAGGAGTCTAATCCGGCCCCTACTTCTTGTACCTCAAAAGGGAAGCATAGTAAG
  GTATCGGATCTCATCAGCCACTTTGAAGGAGGCAGTGTTTTGTCAAGTTACATTGATTTGCAGAAAGATT
  CTACTATGAACCTCAATATTCCTCAAACTCTAGGACAGCCTGGGTTAACCTCCTCACCTCCACGAAAATT
  TCTGCCCCAGCACTCTCCACAGAAGCAGGAAAACGACCCAGATCAGACTCAGGGGCAACATGGTTGTTTG
  GCCAATGGTGTAGTGGCTGCACAAAACCAGATGGAATGTGAAGATGAGAAGGAGACTACTCTTAGCCCAG
  AGATGGCTATTCAGACTGCTGCCGCCTCTCCTGATACACATGTGCTGAATGGAGAAAGAAATGAAACCAT
  CACAGATTCTGCATCATCCATAGCCAATAGTCATGATGAAAATGCTTCTGACAGCAGCTGCAGGACTCCA
  GGGACGGACTTAGGGCTTCCCTCAAAAGAAGGGGAGCCAGGGATGGACGCTGAGCTCCAAGAGAGGGAAA
  ATGGGGTGAACACCATGGGATTGGATACGTTGGACCAGCACCATGAAGTGAAGGAGACTAATGAACAGAA
  ACTTCACAAAATAGCCACTGAACTTTTACTTACAGAAAGAGCTTATGTCAGCCGGCTCGACCTCCTAGAT
  CAGGTATTTTATTGCAAACTATTAGAAGAAGCAAACCGAGGCTCATTTCCTGCAGAGATGGTGAATAAAA
  TCTTTTCTAACATTTCATCAATAAATGCCTTCCATAGTAAATTCCTATTACCTGAGCTGGAGAAACGAAT
  GCAAGAATGGGAAACTACACCCAGAATTGGAGATATCCTGCAAAAGTTGGCGCCATTCCTTAAGATGTAT
  GGAGAATACGTGAAGGGATTTGATAATGCAGTGGAACTGGTTAAAACCATGACAGAGCGTGTTCCCCAGT
  TTAAATCAGTGACTGAAGAGATTCAGAAACAGAAGATCTGTGGAAGCTTAACGCTGCAGCATCACATGCT
  GGAGCCTATTCAGCGCATTCCTCGCTATGAGATGCTCCTGAAGGACTACCTGAAGAAGTTGTCTCCTGAC
  TCCCCAGACTGGAATGATGCAAAAAAGTCACTTGAAATTATATCTACAGCAGCAAGCCATTCTAATAGTG
  CAATAAGAAAAATGGAGAACCTGAAGAAACTTTTAGAAATTTATGAGATGTTGGGAGAAGAAGAGGATAT
  TGTAAATCCCTCAAATGAACTAATAAAAGAAGGACAAATCCTCAAACTAGCAGCTCGGAACACATCAGCA
  CAAGAGCGCTACCTCTTCTTATTCAACAACATGTTGCTATATTGTGTGCCCAGATTCAGCTTGGTTGGCT
  CAAAATTCACAGTTCGAACCAGAGTTGGCATTGATGGAATGAAAATTGTGGAGACTCACAATGAAGAATA
  TCCACACACTTTCCAGATATCTGGGAAAGAAAGAACCCTGGAGCTGCAGGCCAGTTCTGAACAAGACAAG
  GAAGAATGGATCAAGGCCCTTCAAGAAAGTATTGATGCTTTTCATCAAAGGCATGAAACTTTCAGAAATG
  CAATCGCAAAGGAAAATGACATTCCCCTAGAAGTTTCTACTGCTGAGCTGGGAAAACGAGCTCCAAGATG
  GATACGTGATAATGAAGTGACCATGTGTATGAAGTGCAAAGAGTCCTTCAATGCACTGACCAGAAGGCGG
  CATCACTGCCGGGCATGTGGACATGTGGTTTGTTGGAAATGTTCTGACTACAAAGCTCAGCTTGAGTATG
  ATGGTGGAAGATTGAACAAGGTTTGTAAAGACTGTTACCAGATAATAAGTGGATTCACAGACAGTGAAGA
  AAAGAAAAGAAGGGGCATTTTAGAGATTGAATCAGCAGAAGTATCAGGAAATAGTGAGGTGTGCAGTTTC
  CTTCAGTACATGGAAAAGTCAAAGCCTTGGCAGAAAATCTGGTGTGTGATCCCCAAGCAAGACCCCCTTG
  TGCTGTACATGTATGGCGCTCCTCAGGATGTCAGAGCCCAAGCGACCATACCCCTCCTGGGCTACGTTGT
  GGATGATATGCCTAAGAGTGCAGATCTGCCACATAGTTTCAAGCTGACCCAGTCCAAGTCTGTGCATAGC
  TTTGCTGCAGACAATGAGGAACTGAAACAGAAATGGCTGAAAATCATCCTTCTAGCTGTCACAGGTGAGA
  CACCAGATGGCCCAAGTGAGCATCTAGCCACCTTGAACAATCTCCCTGGACCCAAGAAAAAGTCAGAATG
  CTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001301817
• ORF Size: 2664 bp
• Insert Size: 2664
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001301817.1, NP_001288746.1
• RefSeq Size: 8362
• RefSeq ORF: 2664
• Locus ID: 224014
• Gene Summary: This gene is a member of the FYVE, RhoGEF and PH domain containing (FGD) family. The encoded protein is a Cdc42-specific guanine nucleotide exchange factor (GEF) that plays an essential role in regulating the actin cytoskeleton and cell morphology. Disruption of the gene in mouse causes abnormal nerve development and dysmyelination. Mutations in a similar gene in human can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).