Rac2 (BC005455) Mouse Tagged ORF Clone

CAT#: MG201847

Rac2 (GFP-tagged) - Mouse RAS-related C3 botulinum substrate 2 (cDNA clone MGC:6255 IMAGE:3495818)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Rac2
• Synonyms: AI323801|AI452260
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG201847 representing BC005455
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCAGGCCATCAAGTGTGTGGTGGTGGGTGATGGAGCCGTGGGCAAGACGTGTCTTCTCATCAGCTACA
  CCACCAACGCCTTCCCTGGAGAATACATCCCCACTGTATTTGACAACTACTCAGCCAATGTGATGGTGGA
  CAGTAAGCCGGTGAACCTGGGGCTGTGGGATACCGCAGGTCAGGAGGACTATGACCGCCTCCGGCCACTC
  TCCTACCCACAGACAGATGTATTTCTCATCTGCTTCTCGCTAGTCAGCCCAGCCTCCTATGAGAATGTCC
  GTGCCAAGTGGTTCCCTGAGGTACGGCACCACTGCCCCAGCACCCCCATCATCCTGGTGGGTACCAAGCT
  GGACCTTCGCGATGACAAGGACACCATCGAGAAGCTGAAGGAGAAGAAGCTGGCTCCCATCACCTACCCG
  CAGGGCCTGGCACTGGCCAAGGATATTGATTCAGTCAAGTACTTGGAATGTTCTGCACTCACCCAGCGAG
  GCCTGAAGACCGTCTTCGATGAGGCAATCCGCGCAGTCCTCTGCCCACAGCCCACACGACAGCAGAAGCG
  CCCCTGCAGCCTGCTC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG201847 representing BC005455
  Red=Cloning site Green=Tags(s)
  
  MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPL
  SYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYP
  QGLALAKDIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRPCSLL
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: BC005455
• ORF Size: 576 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: BC005455, AAH05455
• RefSeq Size: 1375
• RefSeq ORF: 578
• Locus ID: 19354
• Gene Summary: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase. [UniProtKB/Swiss-Prot Function]