Casp6 (NM_009811) Mouse Tagged ORF Clone

CAT#: MG203708

Casp6 (GFP-tagged) - Mouse caspase 6 (Casp6)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Casp6
• Synonyms: CASP-6; Mch2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG203708 representing NM_009811
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACAGAAACCGATGGCTTCTACAAAAGTAGGGAAGTGTTCGATCCAGCCGAGCAGTACAAGATGGACC
  ACAAGAGGAGAGGAGTTGCCCTCATCTTCAATCACGAGAGGTTCTTTTGGCACCTGACCCTCCCAGAGAG
  GCGGGGCACCAACGCAGACAGAGACAACCTGACTCGCAGGTTTTCAGATCTAGGATTTGAAGTGAAATGC
  TTTAACGACCTCAGAGCAGAAGAACTCCTGCTCAAAATTCACGAGGTGTCGACTTCAAGCCACATAGATG
  CCGATTGCTTCATCTGTGTCTTCCTGAGCCACGGGGAAGGCAACCACGTTTACGCATACGACGCCAAAAT
  TGAAATTCAGACGTTGACTGGCTTGTTCAAAGGAGACAAATGTCAGAGCCTGGTTGGAAAACCCAAGATA
  TTTATCATCCAGGCCTGTCGGGGCAGCCAGCATGACGTACCTGTGGTTCCCCTGGACGTGGTGGATCACC
  AGACAGACAAGCTGGACAACGTGACCCAGGTGGATGCTGCGTCTGTGTACACGCTGCCGGCAGGGGCAGA
  CTTCCTCATGTGCTACTCTGTCGCAGAAGGGTATTACTCTCACCGAGAAACTGTGAATGGCTCCTGGTAC
  ATTCAGGATTTGTGTGAGATGCTGGCGAGGTACGGCAGTTCCCTGGAGTTCACGGAGCTGCTCACGCTGG
  TGAACAGAAAGGTCTCTCAGCGCCGCGTGGACTTCTGCAAAGACCCGGATGCAATCGGCAAGAAGCAGGT
  GCCCTGCTTCGCCTCAATGCTGACCAAAAAGCTGCATTTCTGTCCCAAACCTAGCAAG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG203708 representing NM_009811
  Red=Cloning site Green=Tags(s)
  
  MTETDGFYKSREVFDPAEQYKMDHKRRGVALIFNHERFFWHLTLPERRGTNADRDNLTRRFSDLGFEVKC
  FNDLRAEELLLKIHEVSTSSHIDADCFICVFLSHGEGNHVYAYDAKIEIQTLTGLFKGDKCQSLVGKPKI
  FIIQACRGSQHDVPVVPLDVVDHQTDKLDNVTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWY
  IQDLCEMLARYGSSLEFTELLTLVNRKVSQRRVDFCKDPDAIGKKQVPCFASMLTKKLHFCPKPSK
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_009811
• ORF Size: 828 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_009811.2, NP_033941.2
• RefSeq Size: 1281
• RefSeq ORF: 831
• Locus ID: 12368
• Gene Summary: This gene encodes a member of the cysteine proteases that plays important roles in regulating apoptosis and neurodegeneration. The encoded protein is involved in the transmission of pain and axonal degeneration. Genetic deletion of this gene in mice results in the delay of axon pruning and protects from axon degeneration. [provided by RefSeq, Apr 2015]