Psen2 (NM_011183) Mouse Tagged ORF Clone
CAT#: MG207152
- TrueORF®
Psen2 (GFP-tagged) - Mouse presenilin 2 (Psen2)
"NM_011183" in other vectors (4)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | TurboGFP |
Symbol | Psen2 |
Synonyms | Ad4h; ALG-3; Alg3; PS-2; PS2; Psnl2; STM2 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MG207152 representing NM_011183
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCTCGCATTCATGGCCTCTGACAGCGAGGAAGAGGTGTGTGATGAGCGGACGTCCTTGATGTCAGCCG AGAGCCCCACATCTCGCTCCTGCCAGGAAGGCAGGCCAGGCCCGGAGGATGGAGAGAGCACTGCCCAGTG GAGGACTCAGGAGAGCGAAGAAGACTGTGAAGAGGACCCGGACCGCTACGCATGCAGTGGGGCTCCTGGG CGACCGTCGGGCCTGGAGGAAGAGCTGACCCTCAAGTATGGGGCGAAGCATGTGATCATGCTATTCGTGC CTGTCACGCTGTGTATGATCGTGGTGGTGGCCACTATCAAGTCTGTGCGTTTCTACACTGAGAAGAACGG GCAGCTCATCTACACGCCCTTCACGGAGGACACGCCCTCGGTGGGCCAGCGGCTCCTCAACTCCGTGCTT AACACCCTCATCATGATCAGCGTCATCGTAGTCATGACCATCTTCCTCGTGGTACTCTACAAGTATCGAT GCTACAAGTTCATCCATGGCTGGCTGATCATGTCCTCCCTGATGCTCCTCTTCTTGTTCACCTACATCTA CCTCGGGGAAGTGCTCAAGACCTACAATGTGGCCATGGACTATCCCACACTCTTCCTGGCTGTCTGGAAC TTCGGGGCAGTGGGCATGGTGTGCATCCACTGGAAGGGGCCTCTGGTGCTGCAGCAGGCTTACCTTATTG TGATCAGCGCACTCATGGCCCTGGTGTTCATCAAGTACCTGCCGGAGTGGTCTGCCTGGGTCATCTTGGG TGCCATCTCTGTGTACGATCTCGTGGCCGTGCTGTGCCCCAAAGGGCCACTGAGGATGCTGGTGGAAACT GCCCAGGAGAGAAATGAGCCCATATTTCCTGCCCTGATATACTCATCTGCCATGGTGTGGACGGTGGGCA TGGCAAAGCTGGACCCCTCCTCTCAAGGAGCGCTGCAGCTCCCCTATGACCCAGAGATGGAAGAAGACTC CTACGACAGTTTTGGAGAACCCTCATACCCTGAAGCCTTCGAAGCCCCCCTGCCTGGCTACCCAGGGGAG GAGCTGGAGGAGGAGGAGGAAAGGGGCGTGAAGCTCGGCCTGGGAGACTTCATCTTCTACAGCGTCCTGG TGGGCAAGGCTGCAGCCACTGGCAACGGAGACTGGAACACTACGCTGGCCTGTTTTATCGCCATCCTCAT TGGCTTGTGTCTCACCCTCCTGCTGCTTGCTGTGTTCAAGAAGGCTCTGCCCGCCCTCCCCATCTCCATC ACCTTTGGACTCATCTTCTACTTCTCCACAGACAACCTGGTGCGCCCTTTCATGGACACTCTGGCCTCCC ACCAGCTCTACATC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG207152 representing NM_011183
Red=Cloning site Green=Tags(s) MLAFMASDSEEEVCDERTSLMSAESPTSRSCQEGRPGPEDGESTAQWRTQESEEDCEEDPDRYACSGAPG RPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVL NTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLAVWN FGAVGMVCIHWKGPLVLQQAYLIVISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVET AQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAPLPGYPGE ELEEEEERGVKLGLGDFIFYSVLVGKAAATGNGDWNTTLACFIAILIGLCLTLLLLAVFKKALPALPISI TFGLIFYFSTDNLVRPFMDTLASHQLYI TRTRRLE - GFP Tag - V |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_011183 |
ORF Size | 2023 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_011183.1 |
RefSeq Size | 1954 |
RefSeq ORF | 1347 |
Locus ID | 19165 |
Gene Summary | This gene encodes a member of the presenilin family. Presenilins are catalytic components of the multi-subunit gamma-secretase complex, which mediates critical cellular processes through cleavage of type I transmembrane proteins including Notch receptors and the amyloid precursor protein. The encoded protein contains eight transmembrane domains and is localized to the endoplasmic reticulum, where it may play a role in calcium homeostasis. Following assembly of the gamma-secretase complex, the encoded protein is cleaved into N- and C-terminal fragments and the activated complex is released from the endoplasmic reticulum. Inactivation of this gene results in impaired synaptic function in a mouse model for Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2011] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MR222924 | Psen2 (Myc-DDK-tagged) - Mouse presenilin 2 (Psen2), transcript variant 1 |
USD 350.00 |
|
MG222924 | Psen2 (GFP-tagged) - Mouse presenilin 2 (Psen2) transcript variant 1, (10ug) |
USD 390.00 |
|
MR222924L3 | Lenti ORF clone of Psen2 (Myc-DDK-tagged) - Mouse presenilin 2 (Psen2), transcript variant 1 |
USD 550.00 |
|
MR222924L4 | Lenti ORF clone of Psen2 (mGFP-tagged) - Mouse presenilin 2 (Psen2), transcript variant 1 |
USD 550.00 |
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