Itgb7 (NM_013566) Mouse Tagged ORF Clone

CAT#: MG224242

Itgb7 (GFP-tagged) - Mouse integrin beta 7 (Itgb7), (10ug)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Itgb7
• Synonyms: Ly69
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG224242 representing NM_013566
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGTGGATTCATCAACTGTTCTCATTTTTCTGCTGGTTCTGGGCGGAGGTCAGAGTGAGTTAGATACCA
  AGATTACATCCTCTGGGGAGGCCGCAGAATGGGAGGATCCTGACCTGTCTCTGCAGGGATCCTGCCAGCC
  AGTTCCTTCCTGCCAGAAGTGTATTCTCTCACATCCCAGCTGTGCATGGTGCAAACAACTGAACTTCACT
  GCCTCGGGAGAGGCAGAGGCGAGGCGCTGCGCGCGGCGAGAGGAGCTACTGGCTCGCGGGTGCCCCGCGC
  AGGAGCTAGAGGAGCCGAGAGGCCGCCAGGAGGTGCTGCAGGACAAGCCGCTCAGCCAGGGAGATCGCGG
  CGAGGGGGCCACCCAGCTGGCCCCGCAGCGGATCCGCGTCACGCTGCGACCAGGGGAGCCCCAGAAATTC
  CGGGTCCGCTTCCTCCGAGCTGCGGGGTACCCCGTGGACCTATATTACCTTATGGACCTGAGCTACTCAA
  TGAAGGACGACTTGGAACGTGTGCGCCAGCTAGGGCATGCCCTGCTGGTCAGGCTGCAGGAGGTCACACA
  TTCTGTGCGCATAGGTTTTGGCTCCTTCGTGGACAAAACGGTGCTGCCCTTTGTAAGCACCGTGCCCTCC
  AAGCTTCACCACCCATGCCCCAGCCGACTGGAGCGTTGTCAGCCACCCTTCAGCTTTCACCACGTGCTGT
  CCCTCACCGGGGACGCTCAAGCCTTCGAGAGAGAGGTGGGACGCCAGAATGTCTCTGGCAACCTGGACTC
  ACCCGAAGGCGGCTTTGATGCCATTTTGCAGGCTGCCCTCTGCCAGGAACAGATTGGCTGGAGAAATGTC
  TCCCGTCTTCTAGTGTTCACTTCAGACGATACATTCCACACAGCTGGGGATGGGAAACTGGGTGGCATTT
  TCATGCCCAGCGACGGGCGGTGCCATCTGGACAGCAATGGTGTCTACACGAACAGCGCAGAGTTTGACTA
  TCCCTCTGTGGGTCAAGTAGCCCAGGCCCTCACTGCAGCGAATATCCAACCTATCTTTGCTGTCACCGGT
  GCAACACTGCCTGTGTATCAGGAGCTGAGACAGTTGATTCCCAAGTCTGCTGTCGGGGAGCTGAGTGAGG
  ACTCCAGCAATGTGGTGCAGCTCATCATGGATGCTTATGATAGCCTGTCATCCACTGTGACTCTTGAGCA
  CTCTCCACTCCCACCAGGAGTCAGCATCTCCTTTGAATCTCACTGTAAGGGTCCTGAGAAGACGGAGGGT
  GAGGCTGGGGACCGGGGACAGTGCAATGATGTCCGAGTCAACCAGACGGTGGATTTCTGGGTCACTCTTC
  AAGCTACTCACTGCCTCCCAGAAGCCCACGTCCTACGACTCTGGGCTCTTGGCTTCTCAGAGGAGTTAAC
  TGTGGAGCTGCACACAGTGTGCGACTGTAACTGTGGTGATGCCCAGCCTCACGCTCCCTACTGCAGTGAT
  GGACAGGGGGACCTTCAGTGCGGGATATGCAGCTGTGCCCCTGGCCGTCTTGGTCAGCTGTGTGAATGCT
  CTGAGGCTGACCTGTCCTCCCCAGATTTGGAATCTGGTTGCCGGGCCCCAAACGGGACAGGGCCCCTATG
  CAGCGGGAAGGGTCGATGCCAATGTGGACGCTGCAGCTGCAGTGGGCAGAGCTCTGGGCGTCTGTGCGAG
  TGTGATGATGCCAGCTGTGAGCGACATGAGGGCATCCTCTGTGGAGGCTTTGGCCACTGCCAGTGTGGAG
  TATGTCACTGTCACGCCAACCACACCGGCAGAGCTTGCGAGTGCAGCAAGAGTGTAGACAGCTGTGTCAG
  TCCTGAAGGAGGGCTCTGCAGTGGGCACGGATACTGCAAATGCAACCGTTGCCAGTGCCTGGATGGCTAC
  TACGGGGCTCTGTGTGACCAGTGCCTAGGCTGCAAGTCACCATGTGAGCAGTACAGGGATTGTGCAGAGT
  GCGGGGCATTTGGTACCGGTCCCCTGGCAGCCAACTGTAGTGTGGTCTGTGCTGACGTGAATGTGACCTT
  GACCTTGGCCCCTAACTTGGATGATGGCTGGTGCAAAGAAAGGACAATAGACAACCAGCTGTTCTTCTTC
  CTGGTGGAGCATGCAGCCAGCGGGATCGTACTGAGAGTGAGACCCCAAGAGAAGGGAGTGGATCACACCC
  GTGCCATCATACTGGGCTGCACAGGGGGCATCGTGGCAGTGGGACTAGGGCTGGTTCTGGCTTACCGGCT
  CTCTGTGGAAATCTACGACCGACGGGAGTACAGGCGCTTTGAGAAGGAGCAGCAGCAACTCAACTGGAAG
  CAGGACAACAATCCTCTCTACAAAAGTGCGATCACAACCACTGTCAACCCCCGCTTCCAAGGGACAAACG
  GTCGGTCGCCATCCCTCTCTCTGACCAGGGAAGCAGAC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG224242 representing NM_013566
  Red=Cloning site Green=Tags(s)
  
  MVDSSTVLIFLLVLGGGQSELDTKITSSGEAAEWEDPDLSLQGSCQPVPSCQKCILSHPSCAWCKQLNFT
  ASGEAEARRCARREELLARGCPAQELEEPRGRQEVLQDKPLSQGDRGEGATQLAPQRIRVTLRPGEPQKF
  RVRFLRAAGYPVDLYYLMDLSYSMKDDLERVRQLGHALLVRLQEVTHSVRIGFGSFVDKTVLPFVSTVPS
  KLHHPCPSRLERCQPPFSFHHVLSLTGDAQAFEREVGRQNVSGNLDSPEGGFDAILQAALCQEQIGWRNV
  SRLLVFTSDDTFHTAGDGKLGGIFMPSDGRCHLDSNGVYTNSAEFDYPSVGQVAQALTAANIQPIFAVTG
  ATLPVYQELRQLIPKSAVGELSEDSSNVVQLIMDAYDSLSSTVTLEHSPLPPGVSISFESHCKGPEKTEG
  EAGDRGQCNDVRVNQTVDFWVTLQATHCLPEAHVLRLWALGFSEELTVELHTVCDCNCGDAQPHAPYCSD
  GQGDLQCGICSCAPGRLGQLCECSEADLSSPDLESGCRAPNGTGPLCSGKGRCQCGRCSCSGQSSGRLCE
  CDDASCERHEGILCGGFGHCQCGVCHCHANHTGRACECSKSVDSCVSPEGGLCSGHGYCKCNRCQCLDGY
  YGALCDQCLGCKSPCEQYRDCAECGAFGTGPLAANCSVVCADVNVTLTLAPNLDDGWCKERTIDNQLFFF
  LVEHAASGIVLRVRPQEKGVDHTRAIILGCTGGIVAVGLGLVLAYRLSVEIYDRREYRRFEKEQQQLNWK
  QDNNPLYKSAITTTVNPRFQGTNGRSPSLSLTREAD
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_013566
• ORF Size: 2418 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_013566.2, NP_038594.2
• RefSeq Size: 2696
• RefSeq ORF: 2421
• Locus ID: 16421
• Gene Summary: Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is involved in adhesive interactions of leukocytes. It is a receptor for fibronectin and recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Integrin alpha-4/beta-7 is also a receptor for MADCAM1 and VCAM1. It recognizes the sequence L-D-T in MADCAM1. Integrin alpha-E/beta-7 is a receptor for E-cadherin. [UniProtKB/Swiss-Prot Function]