Nppc (NM_010933) Mouse Tagged ORF Clone

CAT#: MG227595

Nppc (GFP-tagged) - Mouse natriuretic peptide precursor type C (Nppc), (10ug)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Nppc
• Synonyms: CNP; lbab
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG227595 representing NM_010933
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCACCTCTCCCAGCTGATCGCCTGCGCCCTGCTGCTCGCGCTACTCTCGCTCCGGCCCTCTGAAGCCA
  AGCCCGGGACACCACCGAAGGTCCCGAGAACCCCGCCAGGGGAGGAGCTGGCGGATTCCCAGGCAGCTGG
  TGGCAATCAGAAAAAGGGTGACAAGACTCCAGGCAGCGGGGGAGCCAATCTCAAGGGAGACCGATCGCGA
  CTGCTCCGGGACCTGCGTGTGGACACCAAGTCCCGGGCTGCTTGGGCCCGCCTTCTGCACGAGCACCCCA
  ACGCGCGCAAATACAAAGGCGGCAACAAGAAGGGCTTGTCCAAAGGCTGCTTTGGCCTCAAGCTGGACCG
  GATCGGCTCCATGAGCGGTCTGGGATGT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG227595 representing NM_010933
  Red=Cloning site Green=Tags(s)
  
  MHLSQLIACALLLALLSLRPSEAKPGTPPKVPRTPPGEELADSQAAGGNQKKGDKTPGSGGANLKGDRSR
  LLRDLRVDTKSRAAWARLLHEHPNARKYKGGNKKGLSKGCFGLKLDRIGSMSGLGC
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_010933
• ORF Size: 378 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_010933.4, NP_035063.1
• RefSeq Size: 1043
• RefSeq ORF: 381
• Locus ID: 18159
• Gene Summary: This gene encodes a member of the natriuretic peptide family. Natriuretic peptides are involved in the control of blood pressure, extracellular fluid volume and electrolyte homeostasis. The encoded protein also plays a role in sensory neuron bifurcation, and is a critical regulator of endochondral bone growth. The encoded protein is a ligand for the natriuretic peptide receptor B, and is synthesized as a preprohormone which is cleaved to produce a mature peptide. Mutations in this gene are associated with dwarfism resulting from impaired endochondral ossification. [provided by RefSeq, Apr 2011]