Taz (NM_181516) Mouse Tagged ORF Clone

CAT#: MR203448

Taz (Myc-DDK-tagged) - Mouse tafazzin (Taz), nuclear gene encoding mitochondrial protein, transcript variant 2

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Taz
• Synonyms: 5031411C02Rik; 9130012G04Rik; AW107266; AW552613; G4.5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR203448 ORF sequence
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCCCTCCATGTGAAGTGGCCATTCCCCGCGGTGCCCCGGCTCACCTGGACTCTAGCCAGCAGCGTCG
  TCATGGGCCTAGTTGGCACCTACAGCTGCTTCTGGACCAAGTACATGAACCACCTCACCGTGCACAACAA
  GGAAGTGCTGTATGAGCTCATTGAGAACCGAGGCCCTGCCACCCCCCTTATCACCGTCTCCAACCACCAG
  TCTTGCATGGATGACCCTCATCTCTGGGGGATCCTAAAACTCCGCCACATCTGGAACCTGAAGTTGATGC
  GTTGGACCCCAGCAGCTGCAGACATCTGCTTCACCAAGGAGCTGCACTCCCATTTCTTCAGCTTGGGCAA
  ATGTGTGCCTGTGTGTCGAGGAGATGGTGTCTACCAGAAAGGGATGGACTTCATTTTGGAGAAGCTTAAC
  CATGGGGACTGGGTGCACATCTTCCCAGAAGGGAAAGTAAACATGAGTTCTGAGTTCCTGCGCTTCAAAT
  GGGGAATTGGACGGCTGATTGCTGAGTGTCATCTGAATCCCATCATCCTGCCACTGTGGCATGTTGGAAT
  GAATGATGTCCTCCCTAACAGCCCACCCTACTTCCCCCGCTTTGGACAGAAAATCACCGTGCTGATTGGG
  AAGCCCTTCAGTACACTCCCTGTGCTTGAGCGGCTCCGGGCAGAGAACAAGTCAGCTGTGGAGATGCGGA
  AAGCCCTCACAGACTTCATTCAAGAGGAATTCCAGCGGCTGAAGATGCAGGCAGAACAGCTCCACAATCA
  TTTCCAGCCTGGAAGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR203448 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MPLHVKWPFPAVPRLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNKEVLYELIENRGPATPLITVSNHQ
  SCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGVYQKGMDFILEKLN
  HGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG
  KPFSTLPVLERLRAENKSAVEMRKALTDFIQEEFQRLKMQAEQLHNHFQPGR
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_181516
• ORF Size: 789 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_181516.1, NM_181516.2, NM_181516.3, NM_181516.4, NM_181516.5, NM_181516.6, NP_852657.1
• RefSeq Size: 1830
• RefSeq ORF: 789
• Locus ID: 66826
• MW: 30.3 kDa
• Gene Summary: This gene encodes a mitochondrial phospholipid-lysophospholipid transacylase necessary for normal composition and content of cardiolipin. In humans, mutations of this gene result in Barth syndrome, most often characterized by cardioskeletal myopathy, neutropenia and abnormal mitochondria. This gene is distinct from the gene encoding transcriptional coactivator with PDZ binding motif. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]