Fgb (NM_181849) Mouse Tagged ORF Clone

CAT#: MR207713

Fgb (Myc-DDK-tagged) - Mouse fibrinogen beta chain (Fgb)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Fgb
• Synonyms: 2510049G14Rik
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR207713 ORF sequence
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGGCATCTATGGCTGCTGCTGCTATTGTGTGTTTTCTCAGTTCAAACTCAAGCTGCCGATGATGACT
  ACGATGAACCGACGGATAGCTTGGATGCCCGTGGTCATCGACCTGTTGACAGGAGAAAGGAAGAGCCTCC
  TAGCCTAAGACCTGCCCCTCCTCCTATCAGTGGAGGGGGCTATCGAGCCCGTCCAGCCAAGGCTACTGCC
  AACCAGAAGAAAGTAGAACGGAGACCCCCCGATGCAGGAGGCTGTCTTCATGCTGACACAGACATGGGAG
  TGTTGTGTCCTACGGGATGTACATTGCAACAAACGTTGTTAAACCAGGAAAGGCCAATCAAGAGTAGTAT
  TGCTGAGTTAAATAACAACATACAGTCTGTTTCCGATACCTCCTCAGTCACCTTTCAGTACCTGACTCTG
  CTAAAGGACATGTGGAAAAAGAAGCAAGCTCAAGTTAAAGAGAATGAAAATGTCATAAATGAGTACTCCT
  CCATCCTGGAAGATCAGAGATTATATATTGATGAGACTGTGAATGATAATATCCCCCTTAATCTTCGTGT
  GCTCCGCTCAATCCTGGAGGACCTGAGAAGCAAAATACAAAAATTAGAGTCTGACATCTCAGCTCAAATG
  GAATACTGCCGCACTCCATGCACTGTCAGCTGCAACATTCCAGTGGTGTCTGGGAAAGAGTGTGAGGAGA
  TCATTAGGAAGGGAGGTGAGACATCCGAAATGTATCTCATCCAGCCTGACACCTCCATCAAGCCGTACAG
  AGTATACTGTGACATGAAAACAGAAAACGGAGGATGGACAGTCATACAGAACCGTCAGGATGGCAGCGTC
  GACTTTGGCAGGAAATGGGACCCATACAAAAAAGGATTCGGAAATATTGCCACCAATGAAGACGCGAAGA
  AGTACTGTGGCTTGCCAGGTGAATATTGGCTTGGCAATGATAAGATTAGCCAGCTCACCAGGATGGGACC
  CACAGAACTTCTCATTGAAATGGAGGACTGGAAAGGAGACAAGGTGAAGGCACATTATGGAGGCTTCACG
  GTACAGAACGAGGCCAGCAAATACCAAGTCTCAGTGAACAAATACAAAGGGACGGCTGGCAACGCCCTCA
  TGGACGGGGCCTCTCAACTGGTGGGGGAGAACAGAACCATGACCATCCACAACGGCATGTTCTTCAGCAC
  GTACGACAGGGACAACGACGGCTGGGTAACTACGGATCCAAGAAAACAGTGCTCCAAAGAAGATGGTGGT
  GGCTGGTGGTATAACAGATGCCATGCAGCCAATCCAAATGGCAGATACTACTGGGGTGGCCTTTACAGCT
  GGGACATGTCCAAGCACGGCACAGATGATGGTGTGGTGTGGATGAACTGGAAGGGATCGTGGTACTCAAT
  GAGGAGGATGTCTATGAAGATCAGGCCCTTCTTCCCACAGCAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR207713 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MRHLWLLLLLCVFSVQTQAADDDYDEPTDSLDARGHRPVDRRKEEPPSLRPAPPPISGGGYRARPAKATA
  NQKKVERRPPDAGGCLHADTDMGVLCPTGCTLQQTLLNQERPIKSSIAELNNNIQSVSDTSSVTFQYLTL
  LKDMWKKKQAQVKENENVINEYSSILEDQRLYIDETVNDNIPLNLRVLRSILEDLRSKIQKLESDISAQM
  EYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDTSIKPYRVYCDMKTENGGWTVIQNRQDGSV
  DFGRKWDPYKKGFGNIATNEDAKKYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFT
  VQNEASKYQVSVNKYKGTAGNALMDGASQLVGENRTMTIHNGMFFSTYDRDNDGWVTTDPRKQCSKEDGG
  GWWYNRCHAANPNGRYYWGGLYSWDMSKHGTDDGVVWMNWKGSWYSMRRMSMKIRPFFPQQ
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_181849
• ORF Size: 1446 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_181849.1, NM_181849.2, NM_181849.3, NP_862897.1
• RefSeq Size: 1575
• RefSeq ORF: 1446
• Locus ID: 110135
• MW: 54.8 kDa
• Gene Summary: This gene encodes the beta subunit of the coagulation factor fibrinogen, which is a component of the blood clot. The encoded preproprotein is proteolytically processed by thrombin to release an N-terminal fibrinopeptide during the conversion of fibrinogen to insoluble fibrin polymer. The encoded protein interacts with the amyloid beta peptide to form fibrin clots of abnormal structure, and may play an important role in Alzheimer's disease. This gene is located adjacent to the genes encoding fibrinogen alpha and gamma subunits on chromosome 3. [provided by RefSeq, Nov 2015]