Tgfbr1 (NM_009370) Mouse Tagged ORF Clone

CAT#: MR208091L3

Lenti ORF clone of Tgfbr1 (Myc-DDK-tagged) - Mouse transforming growth factor, beta receptor I (Tgfbr1)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Tgfbr1
• Synonyms: Alk-5; ALK5; AU017191; ESK2; TbetaR-I; TbetaRI; TGFR-1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR208091).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_009370
• ORF Size: 1509 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_009370.2, NP_033396.1
• RefSeq Size: 5735
• RefSeq ORF: 1512
• Locus ID: 21812
• Gene Summary: This gene encodes a member of the transforming growth factor beta (TGF-beta) receptor family of proteins. These proteins comprise one component of the TGF-beta signaling pathway, which transduces extracellular signals into gene expression changes to regulate a wide range of cellular responses, including proliferation, migration, differentiation and apoptosis. Homozygous knockout mice for this gene exhibit impaired angiogenesis and embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]