Muc1 (NM_013605) Mouse Tagged ORF Clone

CAT#: MR209607

Muc1 (Myc-DDK-tagged) - Mouse mucin 1, transmembrane (Muc1)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Muc1
• Synonyms: CD227; EMA; Muc-1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR209607 ORF sequence
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACCCCGGGCATTCGGGCTCCTTTCTTCCTGCTGCTACTTCTAGCAAGTCTAAAAGGTTTTCTTGCCC
  TTCCAAGTGAGGAAAACAGTGTCACCTCATCTCAGGACACCAGCAGTTCCTTAGCATCGACTACCACTCC
  AGTCCACAGCAGCAACTCAGACCCAGCCACCAGACCTCCAGGGGACTCCACCAGCTCTCCAGTCCAGAGT
  AGCACCTCTTCTCCAGCCACCAGAGCTCCTGAAGACTCTACCAGTACTGCAGTCCTCAGTGGCACCTCCT
  CCCCAGCCACCACAGCTCCAGTGAACTCCGCCAGCTCTCCAGTAGCCCATGGTGACACCTCTTCCCCAGC
  CACTAGCCTTTCAAAAGACTCCAACAGCTCTCCAGTAGTCCACAGTGGCACCTCTTCAGCTCCGGCCACC
  ACAGCTCCAGTGGATTCCACCAGCTCTCCAGTAGTCCACGGTGGTACCTCGTCCCCAGCCACCAGCCCTC
  CAGGGGACTCCACCAGCTCTCCAGACCATAGTAGCACCTCTTCTCCAGCCACCAGAGCTCCCGAAGACTC
  TACCAGTACTGCAGTCCTCAGTGGCACCTCCTCCCCAGCCACCACAGCTCCAGTGGACTCCACCAGCTCT
  CCAGTAGCCCATGATGACACCTCTTCCCCAGCCACTAGCCTTTCAGAAGACTCCGCCAGCTCTCCAGTAG
  CCCACGGTGGCACCTCTTCTCCAGCCACCAGCCCTCTAAGGGACTCCACCAGTTCTCCAGTCCACAGTAG
  TGCCTCCATCCAAAACATCAAGACTACATCAGACTTAGCTAGCACTCCAGACCACAATGGCACCTCAGTC
  ACAACTACCAGCTCTGCACTGGGCTCAGCCACCAGTCCAGACCACAGTGGTACCTCAACTACAACTAACA
  GCTCTGAATCAGTCTTGGCCACCACTCCAGTTTACAGTAGCATGCCATTCTCTACTACCAAAGTGACGTC
  AGGCTCAGCTATCATTCCAGACCACAATGGCTCCTCGGTGCTACCTACCAGTTCTGTGTTGGGCTCAGCT
  ACCAGTCTAGTCTATAATACCTCTGCAATAGCTACAACTCCAGTCAGCAATGGCACTCAGCCTTCAGTGC
  CAAGTCAATACCCTGTTTCTCCTACCATGGCCACCACCTCCAGCCACAGCACTATTGCCAGCAGCTCTTA
  CTATAGCACAGTACCATTTTCTACCTTCTCCAGTAACAGTTCACCCCAGTTGTCTGTTGGGGTCTCCTTC
  TTCTTCTTGTCTTTTTACATTCAAAACCACCCATTTAATTCTTCTCTGGAAGACCCCAGCTCCAACTACT
  ACCAAGAACTGAAGAGGAACATTTCTGGATTGTTTCTGCAGATTTTTAACGGAGATTTTCTGGGGATCTC
  TAGCATCAAGTTCAGGTCAGGCTCCGTGGTGGTAGAATCGACTGTGGTTTTCCGGGAGGGTACTTTTAGT
  GCCTCTGACGTGAAGTCACAGCTTATACAGCATAAGAAGGAGGCAGATGACTATAATCTGACTATTTCAG
  AAGTCAAAGTGAATGAGATGCAGTTCCCTCCCTCTGCCCAGTCCCGGCCGGGGGTACCAGGCTGGGGCAT
  TGCCCTGCTGGTGCTGGTCTGTATTTTGGTTGCTTTGGCTATCGTCTATTTCCTTGCCCTGGCAGTGTGC
  CAGTGCCGCCGAAAGAGCTATGGGCAGCTGGACATCTTTCCAACCCAGGACACCTACCATCCTATGAGTG
  AATACCCTACCTACCACACTCACGGACGCTACGTGCCCCCTGGCAGTACCAAGCGTAGCCCCTATGAGGA
  GGTTTCGGCAGGTAATGGCAGTAGCAGTCTCTCTTATACCAACCCAGCTGTGGTGACCACTTCTGCCAAC
  TTG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR209607 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MTPGIRAPFFLLLLLASLKGFLALPSEENSVTSSQDTSSSLASTTTPVHSSNSDPATRPPGDSTSSPVQS
  STSSPATRAPEDSTSTAVLSGTSSPATTAPVNSASSPVAHGDTSSPATSLSKDSNSSPVVHSGTSSAPAT
  TAPVDSTSSPVVHGGTSSPATSPPGDSTSSPDHSSTSSPATRAPEDSTSTAVLSGTSSPATTAPVDSTSS
  PVAHDDTSSPATSLSEDSASSPVAHGGTSSPATSPLRDSTSSPVHSSASIQNIKTTSDLASTPDHNGTSV
  TTTSSALGSATSPDHSGTSTTTNSSESVLATTPVYSSMPFSTTKVTSGSAIIPDHNGSSVLPTSSVLGSA
  TSLVYNTSAIATTPVSNGTQPSVPSQYPVSPTMATTSSHSTIASSSYYSTVPFSTFSSNSSPQLSVGVSF
  FFLSFYIQNHPFNSSLEDPSSNYYQELKRNISGLFLQIFNGDFLGISSIKFRSGSVVVESTVVFREGTFS
  ASDVKSQLIQHKKEADDYNLTISEVKVNEMQFPPSAQSRPGVPGWGIALLVLVCILVALAIVYFLALAVC
  QCRRKSYGQLDIFPTQDTYHPMSEYPTYHTHGRYVPPGSTKRSPYEEVSAGNGSSSLSYTNPAVVTTSAN
  L
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_013605
• ORF Size: 1893 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_013605.1, NM_013605.2, NP_038633.1
• RefSeq Size: 2243
• RefSeq ORF: 1896
• Locus ID: 17829
• MW: 64.6 kDa
• Gene Summary: The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, Src and NF-kappaB pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Regulates P53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of P53 and represses P53 activity. [UniProtKB/Swiss-Prot Function]