Smc2 (NM_008017) Mouse Tagged ORF Clone

CAT#: MR211783L4

Lenti ORF clone of Smc2 (mGFP-tagged) - Mouse structural maintenance of chromosomes 2 (Smc2)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Smc2
• Synonyms: 5730502P04Rik; AI255214; AW545314; CAP-E; CAPE; Fin16; SMC-2; Smc2l1
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR211783).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_008017
• ORF Size: 3573 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_008017.4, NP_032043.3
• RefSeq Size: 5455
• RefSeq ORF: 3576
• Locus ID: 14211
• Gene Summary: The protein encoded by this gene is a component of both condensin I and condensin II complexes, and forms a heterodimer with structural maintenance of chromosome 4 (Smc4). This heterodimer is the catalytic subunit for both condensin complexes, and is involved in several processes, including chromosome condensation during mitosis and meiosis, cohesin removal during mitosis and meiosis, and single-strand break (SSB) repair. Reduced expression of this gene results in chromosome segregation defects during mitosis and meiosis, with a more severe defect observed in embryonic stem cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]