Smox (NM_001177836) Mouse Tagged ORF Clone

CAT#: MR219790

Smox (Myc-DDK-tagged) - Mouse spermine oxidase (Smox), transcript variant 5

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Smox
• Synonyms: B130066H01Rik; PAO; PAOh1; SMO
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR219790 representing NM_001177836
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCAAAGTTGTGAATCCAGTGGCGACAGTGCGGATGACCCTCTCAGTCGTGGCCTACGGAGAAGGGGAC
  AGCCTCGTGTGGTGGTGATCGGTGCTGGCTTGGCTGGCCTGGCTGCAGCTAGAGCCCTTCTGGAGCAGGG
  CTTCACGGATGTCACTGTGCTTGAGGCTTCCAGCCACATTGGGGGCCGTGTGCAGAGTGTGAGGCTTGGA
  GACACCACCTTTGAGCTGGGAGCCACCTGGATCCATGGATCCCACGGGAATCCTATCTATCAACTAGCAG
  AAGCCAATGGCCTTTTGGAAGAGACAACAGATGGGGAGCGCAGTGTGGGCCGCATCAGCCTTTACTCCAA
  GAATGGCGTGGCCTGCTACCTTACCAACCGTGGCTGCCGCATCCCCAAGGACGTGGTTGAGGAATTCAGC
  GATTTATACAACGAGGTCTATAACATGACCCAGGAGTTCTTCCGGCATGGTAAACCAGTCAATGCCGAGA
  GTCAGAACAGCGTCGGGGTGTTCACCCGGGAGAAGGTGCGGAATCGCATCAGGGATGACCCTGACGACAC
  AGAGGCCACCAAGCGCCTGAAGCTCGCCATGATCCAGCAGTACCTGAAGGTGGAGAGCTGTGAGAGCAGC
  TCCCACAGCATAGATGAGGTGTCCCTGAGCGCCTTTGGAGAATGGACGGAGATCCCAGGCGCCCATCACA
  TCATCCCCTCGGGCTTCATGCGAGTTGTGGAGCTGCTGGCTGAGGGCATTCCTCCACATGTCATCCAGTT
  GGGGAAGCCGGTCCGTTGCATCCACTGGGACCAGGCCTCGGCTCACCCCCGGGGTCCTGAGATCGAGCCC
  CGTGAGCGCTATGGCCATGTGCTGAGTGGCTGGATCTGTGGGGAGGAGGCTCTTGTCATGGAGAGGTGCG
  ATGACGAGGCTGTAGCTGAGATCTGCACAGAGATGCTTCGACAGTTCACAGGGAACCCCAATATACCAAA
  ACCTAGGCGAATCCTGCGCTCAGCCTGGGGCAGCAACCCATACTTCCGGGGTTCCTATTCCTACACACAG
  GTGGGCTCAAGTGGGGCGGATGTGGAGAAGCTAGCCAAGCCCCTGCCCTACACAGAGAGCTCCAAGACAG
  CGCCCATGCAGGTGCTCTTCTCCGGGGAGGCCACACACCGCAAGTACTACTCCACCACCCACGGTGCTCT
  GCTCTCTGGCCAGCGCGAGGCCGCCCGGCTCATCGAGATGTACCGAGACCTCTTCCAGCAGGGGCCC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR219790 representing NM_001177836
  Red=Cloning site Green=Tags(s)
  
  MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAARALLEQGFTDVTVLEASSHIGGRVQSVRLG
  DTTFELGATWIHGSHGNPIYQLAEANGLLEETTDGERSVGRISLYSKNGVACYLTNRGCRIPKDVVEEFS
  DLYNEVYNMTQEFFRHGKPVNAESQNSVGVFTREKVRNRIRDDPDDTEATKRLKLAMIQQYLKVESCESS
  SHSIDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPPHVIQLGKPVRCIHWDQASAHPRGPEIEP
  RERYGHVLSGWICGEEALVMERCDDEAVAEICTEMLRQFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQ
  VGSSGADVEKLAKPLPYTESSKTAPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYRDLFQQGP
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001177836
• ORF Size: 1257 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001177836.1, NP_001171307.1
• RefSeq Size: 1782
• RefSeq ORF: 1260
• Locus ID: 228608
• MW: 46.8 kDa
• Gene Summary: Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal. [UniProtKB/Swiss-Prot Function]