Matk (NM_010768) Mouse Tagged ORF Clone

CAT#: MR220069

Matk (Myc-DDK-tagged) - Mouse megakaryocyte-associated tyrosine kinase (Matk)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Matk
• Synonyms: CHK; HYL; Ntk; p56ntk
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR220069 representing NM_010768
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCAAGGCGAAGCTCCCGGGTCTCCTGGCTGGCCTTTGAAGGCTGGGAATCTAGGGACCTGCCTCGGG
  TGAGCCCTAGATTGTTCGGAGCTTGGCACCCCGCGCCTGCTGCAGCTAGGATGCCAACGCGCTGGGCCCC
  TGGGACTCAATGCATGACCAAGTGTGAGAACTCTCGCCCCAAGCCCGGTGAGCTAGCCTTTCGAAAGGGT
  GACATGGTGACCATCTTGGAGGCCTGTGAGGACAAGAGCTGGTACCGAGCCAAGCACCATGGCAGTGGGC
  AGGAAGGGCTGCTGGCGGCCGCTGCTCTGCGACAGCGGGAGGCCCTCTCCACAGACCCCAAGCTCAGCCT
  CATGCCATGGTTTCATGGCAAGATCTCCGGCCAGGAAGCCATACAGCAGCTGCAGCCACCCGAGGACGGG
  CTGTTCCTTGTGAGGGAATCAGCTCGTCACCCTGGAGACTATGTCTTGTGTGTCAGTTTCGGCCGTGACG
  TCATCCACTACCGTGTTTTGCATCGAGATGGGCACCTCACCATCGATGAGGCCGTGTGTTTCTGTAACCT
  GATGGACATGGTGGAGCACTACACCAAGGACAAGGGGGCCATCTGCACCAAGCTGGTGAAGCCAAGGAGG
  AAACAGGGCGCAAAGTCTGCAGAGGAGGAGCTCGCCAAGGCTGGCTGGCTACTCGACCTGCAGCATCTGA
  CTCTGGGAGCACAGATTGGAGAGGGGGAGTTTGGAGCCGTCCTACAGGGTGAGTACCTGGGACAGAAGGT
  GGCTGTGAAGAATATCAAGTGTGATGTGACAGCCCAGGCCTTCCTGGATGAGACGGCTGTGATGACGAAG
  CTGCAGCACAGGAACCTAGTGCGACTCCTGGGTGTGATCCTGCACCACGGCTTGTACATTGTCATGGAGC
  ACGTGAGCAAGGGCAACCTGGTGAACTTCCTGCGCACGCGGGGCCGTGCTCTTGTGAGCACCTCTCAGCT
  TCTGCAGTTTGCTCTTCATGTTGCTGAAGGCATGGAATACCTGGAGAGCAAGAAGCTGGTGCACCGGGAC
  CTGGCTGCTCGGAACATCCTGGTCTCTGAGGACTTGGTGGCCAAGGTCAGTGACTTTGGCTTAGCCAAGG
  CAGAGCGCAAGGGGCTGGACTCAAGCCGGCTGCCAGTCAAGTGGACGGCACCTGAGGCTCTCAAAAACGG
  GCGGTTCTCCAGCAAGTCGGATGTCTGGAGTTTTGGGGTGCTGTTGTGGGAAGTCTTCTCTTATGGAAGA
  GCCCCATACCCCAAGATGTCGCTAAAGGAGGTTTCAGAGGCTGTGGAGAAGGGTTACCGCATGGAGCCCC
  CCGATGGCTGCCCAGGCTCTGTGCACACCCTCATGGGTAGCTGCTGGGAGGCAGAGCCTGCGCGCCGACC
  ACCCTTCCGCAAAATAGTGGAGAAGCTGGGCCGTGAGCTCCGCAGTGTGGGTGTCTCGGCCCCCGCTGGG
  GGACAGGAGGCTGAGGGCTCAGCTCCCACACGGAGCCAGGACCCC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR220069 representing NM_010768
  Red=Cloning site Green=Tags(s)
  
  MARRSSRVSWLAFEGWESRDLPRVSPRLFGAWHPAPAAARMPTRWAPGTQCMTKCENSRPKPGELAFRKG
  DMVTILEACEDKSWYRAKHHGSGQEGLLAAAALRQREALSTDPKLSLMPWFHGKISGQEAIQQLQPPEDG
  LFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTIDEAVCFCNLMDMVEHYTKDKGAICTKLVKPRR
  KQGAKSAEEELAKAGWLLDLQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTK
  LQHRNLVRLLGVILHHGLYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRD
  LAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGR
  APYPKMSLKEVSEAVEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRKIVEKLGRELRSVGVSAPAG
  GQEAEGSAPTRSQDP
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_010768
• ORF Size: 1515 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_010768.1, NM_010768.2, NP_034898.1
• RefSeq Size: 1734
• RefSeq ORF: 1518
• Locus ID: 17179
• MW: 56.6 kDa
• Gene Summary: Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. [UniProtKB/Swiss-Prot Function]