Cbfb (NM_001161456) Mouse Tagged ORF Clone

CAT#: MR222350

Cbfb (Myc-DDK-tagged) - Mouse core binding factor beta (Cbfb), transcript variant 2

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Cbfb
• Synonyms: AI893578; PEA2; Pebp2; PEBP2b; Pebpb2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR222350 representing NM_001161456
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCGCGCGTCGTCCCGGACCAGAGGAGCAAGTTCGAGAACGAGGAGTTCTTCAGGAAGCTGAGCCGCG
  AGTGCGAGATTAAGTACACGGGCTTCAGGGACCGGCCCCACGAGGAGCGCCAGACACGCTTCCAGAACGC
  CTGCCGCGACGGTCGCTCGGAGATCGTATACTTGAAGGCTCCCATGATTCTGAATGGAGTGTGTGTTATA
  TGGAAGGGCTGGATTGATCTCCACAGATTGGATGGTATGGGTTGCCTGGAGTTTGATGAGGAGCGAGCCC
  AGCAGGAAGATGCATTAGCACAACAGGCCTTTGAAGAGGCTCGAAGAAGAACTCGAGAATTTGAGGATAG
  AGACAGGTCTCACCGGGAGGAAATGGAGGCAAGAAGACAGCAAGACCCTAGTCCTGGTTCTAACTTAGGT
  GGCGGTGATGATCTCAAACTTCGT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR222350 representing NM_001161456
  Red=Cloning site Green=Tags(s)
  
  MPRVVPDQRSKFENEEFFRKLSRECEIKYTGFRDRPHEERQTRFQNACRDGRSEIVYLKAPMILNGVCVI
  WKGWIDLHRLDGMGCLEFDEERAQQEDALAQQAFEEARRRTREFEDRDRSHREEMEARRQQDPSPGSNLG
  GGDDLKLR
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001161456
• ORF Size: 444 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001161456.1, NP_001154928.1
• RefSeq Size: 2776
• RefSeq ORF: 447
• Locus ID: 12400
• MW: 18.1 kDa
• Gene Summary: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. CBFB enhances DNA binding by RUNX1. [UniProtKB/Swiss-Prot Function]