Adam19 (NM_009616) Mouse Tagged ORF Clone

CAT#: MR222929

Adam19 (Myc-DDK-tagged) - Mouse a disintegrin and metallopeptidase domain 19 (meltrin beta) (Adam19)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Adam19
• Synonyms: AL024287; MADDAM; Mltnb; MTLNB
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR222929 representing NM_009616
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCCGGGCGCGCGGGCGTCGCCCGGTTCTGCTTGCTGGCTCTCGCTCTGCAGCTACATTGGCCGCTGG
  CGGCGTGCGAGCCGGGATGGACCACAAGAGGAAGCCAAGAAGGTAGCCCTCCGCTACAGCATGAACTCAT
  AATACCTCAGTGGCGGACTTCAGAAAGCCCTGGGAGAGGAAAGCATCCACTCAGAGCAGAGCTCAGGGTC
  ATGGCTGAAGGGCGAGAGCTGATCCTAGACCTGGAGAAGAACGAGCACCTTTTTGCTCCAGCCTACACAG
  AAACCTGCTACACTGCAAGTGGCAATCCTCAAACCAGCACGCTGAAGTCTGAGGATCACTGCTTTTACCA
  CGGGACTGTGAGGGACGTGGATGAGTCCAGTGTCACGCTCAGCACCTGCCGGGGAATTAGAGGACTGATT
  ATAGTGAGAAGTAACCTCAGCTACATCATCGAGCCCGTCCCTAACAGCGACAGCCAACACCGTATTTACA
  GATCCGAACATCTCACGCTGCCCCCGGGGAACTGTGGGTTCGAGCACTCCGGGCCCACCTCGAAGGACTG
  GGCCCTTCAGTTTACACATCAGACCAAAAAGCAACCTCGCAGAATGAAACGGGAAGATCTACACTCTATG
  AAGTACGTGGAGCTTTACCTGGTGGCTGATTATGCAGAGTTTCAGAAGAATCGACATGACCAGGATGCCA
  CCAAACGCAAGCTCATGGAGATTGCCAACTATGTTGATAAGTTTTACCGCTCCCTGAACATCCGAATTGC
  ACTTGTCGGCTTGGAGGTGTGGACGCATGGGGATAAGTGTGAAGTTTCAGAGAATCCCTACTCTACCCTC
  TGGTCCTTTCTTAGTTGGAGGCGCAAGCTGCTTGCTCAGAAGAGCCATGACAATGCTCAGCTAATCACGG
  GCAGGTCCTTCCAAGGCACCACCATTGGCCTGGCCCCCCTCATGGCCATGTGCTCCGTGTACCAGTCTGG
  AGGAGTTAGCATGGACCACTCCGAGAATGCCATTGGTGTAGCCTCCACTGTGGCCCATGAGATTGGCCAC
  AACTTTGGCATGAGCCATGATTCTGCACACTGCTGTTCTGCCAGTGCAGCCGATGGCGGCTGCATCATGG
  CCGCCGCCACCGGGCACCCTTTCCCCAAAGTGTTCAGTTGGTGTAACAGGAAGGAGCTGGACAGGTATCT
  GCAGACAGGAGGAGGGATGTGTCTCTCCAACATGCCGGACACTAGGACGCTGTATGGAGGCCGGAGGTGT
  GGCAACGGGTACCTGGAAGACGGTGAAGAATGTGACTGTGGAGAAGAGGAGGAATGTAAGAACCCTTGCT
  GCAATGCCTCCAACTGCACTCTGAAGGAAGGGGCAGAGTGTGCCCATGGTTCCTGCTGCCACCAGTGCAA
  GCTGGTGGCTCCTGGAACCCAGTGTCGGGAGCAGGTTCGGCAATGTGACCTCCCCGAGTTCTGCACCGGC
  AAGTCTCCCCACTGCCCCACCAACTATTATCAGATGGATGGCACCCCCTGCGAGGGTGGCCAGGCCTACT
  GCTACAACGGCATGTGCCTCACTTACCAGGAACAGTGCCAGCAGCTGTGGGGACCTGGAGCCCGGCCTGC
  CCTCGATCTTTGCTTTGAGAGGGTGAATGCTGCTGGTGACACCTATGGAAACTGTGGCAAGGGCTTGAAT
  GGCCAATACAGGAAGTGCAGTCCCAGGGATGCCAAGTGTGGGAAGATTCAGTGCCAGAGCACCCAGGCCC
  GGCCCCTGGAATCCAACGCAGTATCTATTGACACCACCATCACCTTGAACGGGAGGCGGATCCACTGTCG
  GGGCACCCACGTCTACCGGGGTCCTGAGGAGGAGGAAGGGGAAGGTGACATGCTGGACCCAGGGCTGGTG
  ATGACTGGAACCAAGTGTGGCCACAACCATATTTGCTTCGAGGGGCAGTGCAGGAACACCTCCTTCTTTG
  AGACGGAAGGCTGTGGGAAAAAGTGCAATGGCCACGGGGTCTGCAACAACAACAAGAACTGTCATTGCTT
  CCCTGGCTGGTCTCCACCTTTCTGTAACACCCCGGGAGATGGTGGCAGCGTCGACAGTGGTCCTTTGCCC
  CCTAAGAGTGTGGGTCCCGTGATCGCTGGGGTGTTTTCAGCTCTCTTCGTGTTGGCAGTTCTGGTGCTAC
  TGTGTCACTGCTACAGACAGAGCCACAAACTGGGCAAACCCTCGGCTCTCCCTTTCAAGCTGCGGCATCA
  GTTCAGTTGTCCCTTCAGGGTATCTCAGAGTGGTGGAACTGGCCATGCCAACCCAACTTTCAAGTTGCAG
  ACCCCCCAGGGCAAGCGAAAGGTGACTAACACCCCTGAATCCCTCCGGAAGCCGTCCCACCCCCCTCCCC
  GGCCCCCTCCAGACTACCTGCGCGTTGAATCGCCACCTGCACCATTGCCGGCACATCTGAACAGGGCTGC
  TGGGAGCTCCCCAGAAGCTGGGGCTCGAATAGAAAGAAAGGAGTCAGCCAGGAGGCCTCCCCCAAGCCGA
  CCCATGCCCCCTGCACCTAACTGCCTACTGTCCCAGGACTTCTCCAGGCCTCGACCACCTCAGAAGGCAC
  TCCCAGCCAATCCGGTGCCAGGCCAAAGGACCGGTCCCAGGTCAGGAGGCACCTCCCTGCTTCAGCCCCC
  TACTTCTGGTCCTCAGCCCCCCAGGCCTCCAGCAGTGCCTGTTCCAAAGCTACCCGAGTACCGATCACAG
  AGGGTTGGAGCAATAATTAGCTCCAAGATC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR222929 representing NM_009616
  Red=Cloning site Green=Tags(s)
  
  MPGRAGVARFCLLALALQLHWPLAACEPGWTTRGSQEGSPPLQHELIIPQWRTSESPGRGKHPLRAELRV
  MAEGRELILDLEKNEHLFAPAYTETCYTASGNPQTSTLKSEDHCFYHGTVRDVDESSVTLSTCRGIRGLI
  IVRSNLSYIIEPVPNSDSQHRIYRSEHLTLPPGNCGFEHSGPTSKDWALQFTHQTKKQPRRMKREDLHSM
  KYVELYLVADYAEFQKNRHDQDATKRKLMEIANYVDKFYRSLNIRIALVGLEVWTHGDKCEVSENPYSTL
  WSFLSWRRKLLAQKSHDNAQLITGRSFQGTTIGLAPLMAMCSVYQSGGVSMDHSENAIGVASTVAHEIGH
  NFGMSHDSAHCCSASAADGGCIMAAATGHPFPKVFSWCNRKELDRYLQTGGGMCLSNMPDTRTLYGGRRC
  GNGYLEDGEECDCGEEEECKNPCCNASNCTLKEGAECAHGSCCHQCKLVAPGTQCREQVRQCDLPEFCTG
  KSPHCPTNYYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPALDLCFERVNAAGDTYGNCGKGLN
  GQYRKCSPRDAKCGKIQCQSTQARPLESNAVSIDTTITLNGRRIHCRGTHVYRGPEEEEGEGDMLDPGLV
  MTGTKCGHNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNKNCHCFPGWSPPFCNTPGDGGSVDSGPLP
  PKSVGPVIAGVFSALFVLAVLVLLCHCYRQSHKLGKPSALPFKLRHQFSCPFRVSQSGGTGHANPTFKLQ
  TPQGKRKVTNTPESLRKPSHPPPRPPPDYLRVESPPAPLPAHLNRAAGSSPEAGARIERKESARRPPPSR
  PMPPAPNCLLSQDFSRPRPPQKALPANPVPGQRTGPRSGGTSLLQPPTSGPQPPRPPAVPVPKLPEYRSQ
  RVGAIISSKI
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_009616
• ORF Size: 2760 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_009616.1, NM_009616.2, NM_009616.3, NM_009616.4, NP_033746.1
• RefSeq Size: 6388
• RefSeq ORF: 2763
• Locus ID: 11492
• MW: 101.3 kDa
• Gene Summary: This gene encodes a cell surface glycoprotein and member of the ADAM (a disintegrin and metalloproteinase) family of endopeptidases. The encoded protein may play a role in the ectodomain shedding of neuregulin proteins. Homozygous knockout mice for this gene exhibit heart development defects and perinatal lethality. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that undergoes proteolytic processing to generate a mature protein product. [provided by RefSeq, Aug 2015]