Adnp (NM_009628) Mouse Tagged ORF Clone

CAT#: MR223066

Adnp (Myc-DDK-tagged) - Mouse activity-dependent neuroprotective protein (Adnp)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Adnp
• Synonyms: AA589558; mKIAA0784
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR223066 representing NM_009628
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTTCCAACTTCCTGTCAACAATCTTGGCAGTTTAAGAAAAGCCCGGAAAACTGTGAAAAAAATACTTA
  GTGACATTGGGTTGGAATACTGTAAAGAACATATAGAAGATTTTAAACAGTTTGAACCTAATGACTTTTA
  TTTGAAAAACACTACATGGGAGGATGTAGGACTGTGGGACCCTTCTCTTACGAAAAATCAGGACTATCGG
  ACAAAACCTTTTTGCTGCAGTGCTTGTCCGTTTTCCTCAAAATTCTTCTCTGCCTACAAAAGTCATTTCC
  GGAATGTCCATAGTGAAGACTTTGAAAATAGGATTCTCCTTAACTGCCCTTACTGTACCTTCAATGCAGA
  TAAAAAGACTTTGGAAACACACATTAAAATATTTCATGCTCCAAACTCCAGCGCACCAAGTAGCAGCCTC
  AGCACTTTCAAAGATAAAAACAAAAACGATGGCCTTAAACCTAAGCAGGCTGACAATGTAGAGCAAGCCG
  TGTATTACTGCAAGAAGTGCACTTACCGAGACCCTCTCTACGAGATCGTCAGGAAGCACATCTACAGGGA
  ACATTTTCAACACGTGGCAGCACCCTACATAGCAAAAGCAGGAGAAAAATCACTCAATGGTGCAGTCTCC
  CTGGGCACAAATGCCCGAGAGGAGTGTAACATCCACTGCAAGCGATGCCTTTTCATGCCCAAGTCCTATG
  AAGCTTTGGTACAGCATGTCATTGAGGACCATGAACGGATAGGCTATCAGGTCACTGCCATGATCGGACA
  CACAAATGTTGTAGTTCCCCGAGCCAAGCCCTTGATGCTGATAGCTCCCAAACCTCAAGACAAAAAGGGC
  ATGGGACTCCCACCACGAATCAGCTCCCTTGCTTCTGGAAATGTCCGGTCGTTGCCATCACAGCAGATGG
  TAAACCGATTGTCAATACCAAAGCCCAACTTAAATTCAACGGGAGTCAACATGATGTCCAATGTTCACCT
  GCAGCAAAACAACTATGGAGTCAAATCTGTGGGCCAGAGCTATGGTGTTGGCCAGTCAGTGAGGCTGGGA
  CTAGGTGGCAATGCTCCAGTTTCCATCCCTCAACAGTCTCAGTCCGTGAAACAGTTACTTCCAAGTGGGA
  ATGGGAGGTCTTTTGGGCTAGGTGCTGAGCAGAGGCCCCCAGCAGCAGCCAGGTACTCCCTGCAGACTGC
  CAACACCTCTCTACCCCCAGGCCAAGTGAAGTCTCCCTCTGTGTCTCAGTCACAGGCATCTAGAGTATTA
  GGTCAGTCCAGTTCTAAACCTCCACCAGCCGCCACAGGCCCTCCTCCAAGCAACCACTGTGCCACTCAGA
  AGTGGAAAATCTGTACAATCTGTAACGAGCTTTTCCCTGAGAATGTCTATAGCGTTCACTTCGAAAAGGA
  GCATAAAGCTGAGAAAGTCCCAGCCGTAGCTAACTACATTATGAAAATACACAATTTTACTAGCAAATGC
  CTCTACTGTAATCGCTATTTGCCTACAGATACCCTACTCAACCATATGTTAATTCATGGTCTGTCTTGTC
  CGTATTGCCGTTCCACCTTCAATGATGTAGAGAAGATGGCAGCACACATGCGAATGGTTCATATTGATGA
  AGAGATGGGGCCTAAAACGGATTCTACTTTGAGCTTTGATTTGACATTGCAACAGGGCAGTCACACCAAC
  ATTCATCTCCTGGTGACCACATACAACCTGAGGGATGCCCCGGCTGAATCAGTTGCTTACCATGCCCAAA
  ATAATGCCCCAGTTCCTCCAAAGCCACAACCAAAAGTTCAGGAAAAAGCAGATGTCCCGGTTAAAAGTTC
  ACCTCAAGCTGCAGTGCCCTATAAAAAAGATGTTGGGAAGACCCTTTGCCCTCTTTGCTTTTCAATACTA
  AAAGGACCCATATCTGATGCACTTGCACATCATTTACGAGAAAGACACCAAGTTATTCAGACAGTTCATC
  CGGTTGAGAAAAAGCTAACTTACAAATGTATCCATTGCCTTGGTGTGTATACTAGCAACATGACAGCCTC
  AACCATCACTCTGCATCTAGTCCACTGCAGGGGTGTTGGAAAAACCCAGAATGGCCAGGACAAGACAAAC
  GCACCTTCTCGGCTCAATCAGTCTCCAGGCCTGGCCCCTGTGAAGCGCACGTATGAGCAGATGGAGTTTC
  CACTGCTAAAAAAGCGGAAGCTGGAGGAGGATGCTGATTCCCCTAGCTGCTTTGAAGAGAAGCCAGAAGA
  GCCTGTTGTTTTAGCTTTAGACCCCAAGGGTCATGAAGATGATTCTTATGAGGCTAGGAAAAGCTTTCTC
  ACAAAGTACTTCAACAAACAGCCCTATCCCACCAGGAGAGAAATTGAGAAGTTAGCTGCCAGTCTATGGC
  TATGGAAGAGTGACATTGCCTCCCATTTCAGTAACAAGAGGAAGAAGTGTGTCCGCGACTGTGAAAAGTA
  CAAGCCTGGTGTGCTGCTAGGTTTTAACATGAAAGAATTAAATAAAGTCAAACACGAGATGGATTTTGAT
  GCTGAGTGGCTGTTTGAAAATCACGATGAGAAAGACTCAAGAGTCAATGCTAGCAAGACTGTTGACAAAA
  AGCATAACCTTGGGAAAGAAGATGATAGCTTCTCAGATAGTTTTGAACATTTGGAAGAAGAATCCAATGG
  AAGCGGGAGTCCTTTTGACCCTGTCTTTGAAGTTGAGCCTAAAATTCCCAGTGATAATTTAGAGGAGCCT
  GTACCGAAGGTTATTCCGGAAGGTGCTTTGGAATCTGAGAAGCTAGACCAAAAAGAGGAGGAGGAGGAGG
  AGGAGGAGGAGGATGGTTCAAAATATGAAACTATCCATTTGACTGAGGAACCAGCCAAATTAATGCATGA
  TGCCTCTGATAGTGAGGTAGACCAAGATGATGTAGTTGAGTGGAAAGATGGTGCTTCACCATCTGAGAGT
  GGGCCTGGTTCCCAACAAATCTCAGACTTTGAGGATAATACATGTGAAATGAAACCAGGAACCTGGTCTG
  ATGAGTCTTCCCAGAGTGAAGATGCAAGGAGCAGTAAGCCAGCTGCCAAAAAAAAGGCTACAGTGCAAGA
  TGACACAGAGCAGTTAAAATGGAAGAATAGTTCCTATGGAAAAGTTGAAGGGTTTTGGTCCAAGGACCAG
  TCACAGTGGGAAAATGCATCTGAGAATGCAGAGCGCTTACCAAACCCACAGATTGAGTGGCAGAATAGCA
  CAATTGACAGTGAGGACGGGGAGCAGTTTGACAGCATGACTGACGGAGTTGCTGATCCCATGCATGGCAG
  CTTAACTGGAGTGAAGCTGAGCAGCCAGCAAGCC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR223066 representing NM_009628
  Red=Cloning site Green=Tags(s)
  
  MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYR
  TKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNSSAPSSSL
  STFKDKNKNDGLKPKQADNVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYIAKAGEKSLNGAVS
  LGTNAREECNIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRAKPLMLIAPKPQDKKG
  MGLPPRISSLASGNVRSLPSQQMVNRLSIPKPNLNSTGVNMMSNVHLQQNNYGVKSVGQSYGVGQSVRLG
  LGGNAPVSIPQQSQSVKQLLPSGNGRSFGLGAEQRPPAAARYSLQTANTSLPPGQVKSPSVSQSQASRVL
  GQSSSKPPPAATGPPPSNHCATQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKC
  LYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDLTLQQGSHTN
  IHLLVTTYNLRDAPAESVAYHAQNNAPVPPKPQPKVQEKADVPVKSSPQAAVPYKKDVGKTLCPLCFSIL
  KGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTN
  APSRLNQSPGLAPVKRTYEQMEFPLLKKRKLEEDADSPSCFEEKPEEPVVLALDPKGHEDDSYEARKSFL
  TKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFD
  AEWLFENHDEKDSRVNASKTVDKKHNLGKEDDSFSDSFEHLEEESNGSGSPFDPVFEVEPKIPSDNLEEP
  VPKVIPEGALESEKLDQKEEEEEEEEEDGSKYETIHLTEEPAKLMHDASDSEVDQDDVVEWKDGASPSES
  GPGSQQISDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATVQDDTEQLKWKNSSYGKVEGFWSKDQ
  SQWENASENAERLPNPQIEWQNSTIDSEDGEQFDSMTDGVADPMHGSLTGVKLSSQQA
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_009628
• ORF Size: 3324 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_009628.2, NM_009628.3, NP_033758.2
• RefSeq Size: 4953
• RefSeq ORF: 3327
• Locus ID: 11538
• MW: 124.3 kDa
• Gene Summary: This gene encodes a member of a protein family characterized by nine zinc finger motifs followed by a homeobox domain. In vitro studies demonstrate that the encoded protein interacts with the brahma-related gene1-associated or hBRM factors (BAF) gene expression regulating complex, components of the protein translation machinery, and microtubule-associated proteins. This gene has been implicated in neuroprotection through various processes that include chromatin remodeling, splicing, cytoskeletal reorganization, and autophagy. Homozygous mutant knockout mice display embryonic lethality with defects in neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]