C1qa (NM_007572) Mouse Tagged ORF Clone

CAT#: MR225506

C1qa (Myc-DDK-tagged) - Mouse complement component 1, q subcomponent, alpha polypeptide (C1qa)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: C1qa
• Synonyms: Adic; AI255395; C1q
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR225506 representing NM_007572
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGACCTCTCAGGGATGGCTGGTGGCCTGTGTGCTGACCATGACCCTAGTATGGACAGTGGCTGAAG
  ATGTCTGCCGAGCACCCAACGGGAAGGATGGGGCTCCAGGAAATCCTGGCCGCCCGGGGAGGCCGGGTCT
  CAAAGGAGAGAGAGGGGAGCCAGGAGCTGCTGGCATCCGGACTGGTATCCGAGGTTTTAAAGGAGACCCA
  GGGGAATCTGGCCCCCCTGGCAAACCTGGCAATGTGGGGCTCCCAGGTCCCAGTGGTCCCCTGGGGGACA
  GCGGCCCCCAAGGACTGAAGGGCGTGAAAGGCAATCCAGGCAATATCAGGGACCAGCCCCGGCCAGCTTT
  CTCAGCCATTCGGCAGAACCCAATGACGCTTGGCAACGTGGTTATCTTTGACAAGGTCCTCACCAACCAG
  GAGAGTCCATACCAGAACCACACGGGTCGCTTCATCTGTGCAGTGCCCGGCTTCTATTACTTCAACTTCC
  AAGTGATCTCCAAGTGGGACCTTTGTCTGTTTATCAAGTCTTCCTCCGGGGGCCAGCCCAGGGATTCCCT
  GAGTTTCTCTAACACCAACAACAAGGGGCTCTTTCAGGTGTTAGCAGGGGGCACCGTGCTTCAGCTGCGA
  CGAGGGGACGAGGTGTGGATCGAAAAGGACCCCGCAAAGGGTCGCATTTACCAGGGCACTGAAGCCGACA
  GCATCTTCAGCGGATTCCTCATTTTCCCCTCGGCC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR225506 representing NM_007572
  Red=Cloning site Green=Tags(s)
  
  METSQGWLVACVLTMTLVWTVAEDVCRAPNGKDGAPGNPGRPGRPGLKGERGEPGAAGIRTGIRGFKGDP
  GESGPPGKPGNVGLPGPSGPLGDSGPQGLKGVKGNPGNIRDQPRPAFSAIRQNPMTLGNVVIFDKVLTNQ
  ESPYQNHTGRFICAVPGFYYFNFQVISKWDLCLFIKSSSGGQPRDSLSFSNTNNKGLFQVLAGGTVLQLR
  RGDEVWIEKDPAKGRIYQGTEADSIFSGFLIFPSA
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_007572
• ORF Size: 735 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007572.1, NM_007572.2, NP_031598.2
• RefSeq Size: 1082
• RefSeq ORF: 738
• Locus ID: 12259
• MW: 26.4 kDa
• Gene Summary: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. [UniProtKB/Swiss-Prot Function]