Il7r (NM_008372) Mouse Tagged ORF Clone

CAT#: MR226637

Il7r (Myc-DDK-tagged) - Mouse interleukin 7 receptor (Il7r)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Il7r
• Synonyms: CD127; IL-7Ralpha
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR226637 representing NM_008372
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGATGGCTCTGGGTAGAGCTTTCGCTATAGTTTTCTGCTTAATTCAAGCTGTTTCTGGAGAAAGTGGAA
  ATGCCCAGGATGGAGACCTAGAAGATGCAGACGCGGACGATCACTCCTTCTGGTGCCACAGCCAGTTGGA
  AGTGGATGGAAGTCAACATTTATTGACTTGTGCTTTTAATGACTCAGACATCAACACAGCTAATCTGGAA
  TTTCAAATATGTGGGGCTCTTTTACGAGTGAAATGCCTAACTCTTAACAAGCTGCAAGATATATATTTTA
  TAAAGACATCAGAATTCTTACTGATTGGTAGCAGCAATATATGTGTGAAGCTTGGACAAAAGAATTTAAC
  TTGCAAAAATATGGCTATAAACACAATAGTTAAAGCCGAGGCTCCCTCTGACCTGAAAGTCGTTTATCGC
  AAAGAAGCAAATGATTTTTTGGTGACATTTAATGCACCTCACTTGAAAAAGAAATATTTAAAAAAAGTAA
  AGCATGATGTGGCCTACCGCCCAGCAAGGGGTGAAAGCAACTGGACGCATGTATCTTTATTCCACACAAG
  AACAACAATCCCACAGAGAAAACTACGACCAAAAGCAATGTATGAAATCAAAGTCCGATCCATTCCCCAT
  AACGATTACTTCAAAGGCTTCTGGAGCGAGTGGAGTCCAAGTTCTACCTTCGAAACTCCAGAACCCAAGA
  ATCAAGGAGGATGGGATCCTGTCTTGCCAAGTGTCACCATTCTGAGTTTGTTCTCTGTGTTTTTGTTGGT
  CATCTTAGCCCATGTGCTATGGAAAAAAAGGATTAAACCTGTCGTATGGCCTAGTCTCCCCGATCATAAG
  AAAACTCTGGAACAACTATGTAAGAAGCCAAAAACGAGTCTGAATGTGAGTTTCAATCCCGAAAGTTTCC
  TGGACTGCCAGATTCATGAGGTGAAAGGCGTTGAAGCCAGGGACGAGGTGGAAAGTTTTCTGCCCAATGA
  TCTTCCTGCACAGCCAGAGGAGTTGGAGACACAGGGACACAGAGCCGCTGTACACAGTGCAAACCGCTCG
  CCTGAGACTTCAGTCAGCCCACCAGAAACAGTTAGAAGAGAGTCACCCTTAAGATGCCTGGCTAGAAATC
  TGAGTACCTGCAATGCCCCTCCACTCCTTTCCTCTAGGTCCCCTGACTACAGAGATGGTGACAGAAATAG
  GCCTCCTGTGTATCAAGACTTGCTGCCAAACTCTGGAAACACAAATGTCCCTGTCCCTGTCCCTCAACCA
  TTGCCTTTCCAGTCGGGAATCCTGATACCAGTTTCTCAGAGACAGCCCATCTCCACTTCCTCAGTACTGA
  ATCAAGAAGAAGCGTATGTCACCATGTCTAGTTTTTACCAAAACAAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR226637 representing NM_008372
  Red=Cloning site Green=Tags(s)
  
  MMALGRAFAIVFCLIQAVSGESGNAQDGDLEDADADDHSFWCHSQLEVDGSQHLLTCAFNDSDINTANLE
  FQICGALLRVKCLTLNKLQDIYFIKTSEFLLIGSSNICVKLGQKNLTCKNMAINTIVKAEAPSDLKVVYR
  KEANDFLVTFNAPHLKKKYLKKVKHDVAYRPARGESNWTHVSLFHTRTTIPQRKLRPKAMYEIKVRSIPH
  NDYFKGFWSEWSPSSTFETPEPKNQGGWDPVLPSVTILSLFSVFLLVILAHVLWKKRIKPVVWPSLPDHK
  KTLEQLCKKPKTSLNVSFNPESFLDCQIHEVKGVEARDEVESFLPNDLPAQPEELETQGHRAAVHSANRS
  PETSVSPPETVRRESPLRCLARNLSTCNAPPLLSSRSPDYRDGDRNRPPVYQDLLPNSGNTNVPVPVPQP
  LPFQSGILIPVSQRQPISTSSVLNQEEAYVTMSSFYQNK
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_008372
• ORF Size: 1377 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_008372.1, NM_008372.2, NM_008372.3, NM_008372.4, NP_032398.3
• RefSeq Size: 3227
• RefSeq ORF: 1380
• Locus ID: 16197
• MW: 52.1 kDa
• Gene Summary: Interleukin-7 is a glycoptorein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is a alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. [provided by RefSeq, Jul 2008]