Esr2 (NM_010157) Mouse Tagged ORF Clone

CAT#: MR227140

Esr2 (Myc-DDK-tagged) - Mouse estrogen receptor 2 (beta) (Esr2), transcript variant 2

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Esr2
• Synonyms: ERbeta; ER[b]; Estrb
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR227140 representing NM_010157
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCCATCTGTGCCTCTTCTCACAAGGATTTTTCTCAGCTGAGACCTACGCAAGACATGGAGATCAAAA
  ACTCACCATCAAGCCTTACTTCCCCTGCTTCTTATAACTGTAGCCAGTCCATCCTACCCTTGGAGCATGG
  TCCCATCTATATCCCTTCCTCCTATGTAGAGAGCCGTCACGAATACTCAGCCATGACATTCTACAGTCCT
  GCTGTGATGAACTACAGTGTTCCCAGCAGCACCGGTAACCTGGAAGGTGGGCCTGTTCGCCAGACTGCAA
  GCCCAAATGTGCTATGGCCAACTTCTGGACACCTCTCTCCTTTAGCCACCCACTGCCAATCATCGCTTCT
  CTATGCAGAACCTCAAAAGAGTCCTTGGTGTGAAGCAAGATCACTAGAACACACCTTGCCTGTAAACAGA
  GAGACCCTGAAGAGGAAGCTTGGCGGGAGCGGTTGTGCCAGCCCTGTTACTAGTCCAAGCGCCAAGAGGG
  ATGCTCACTTCTGCGCCGTCTGCAGTGATTATGCATCTGGGTATCATTACGGTGTCTGGTCCTGTGAAGG
  ATGTAAGGCCTTTTTTAAAAGAAGCATTCAAGGACATAATGACTATATCTGTCCAGCCACGAATCAGTGT
  ACCATAGACAAGAACCGGCGTAAAAGCTGCCAGGCCTGCCGACTTCGCAAGTGTTACGAAGTAGGAATGG
  TCAAGTGTGGATCCAGGAGAGAAAGGTGTGGGTACCGAATAGTACGAAGACAGAGAAGTGCCAGCGAGCA
  GGTGCATTGCCTGAACAAAGCCAAGAGAACCAGTGGGCACACACCCCGGGTGAAGGAGCTACTGCTGAAC
  TCTCTGAGTCCCGAGCAGCTGGTGCTCACCCTGCTGGAAGCTGAGCCACCCAATGTGCTAGTGAGCCGTC
  CCAGCATGCCCTTCACCGAGGCCTCCATGATGATGTCCCTCACGAAGCTGGCTGACAAGGAACTGGTGCA
  CATGATTGGCTGGGCCAAGAAAATCCCTGGCTTTGTGGAGCTCAGCCTGTTGGACCAAGTCCGCCTCTTG
  GAAAGCTGCTGGATGGAGGTGCTGATGGTGGGGCTGATGTGGCGCTCCATCGACCACCCCGGCAAGCTCA
  TCTTTGCTCCAGACCTCGTTCTGGACAGGGATGAGGGGAAGTGCGTGGAAGGGATTCTGGAAATCTTTGA
  CATGCTCCTGGCGACGACGGCACGGTTCCGTGAGTTAAAACTGCAGCACAAAGAATATCTGTGTGTGAAG
  GCCATGATTCTCCTCAACTCCAGTATGTACCCCTTGGCTACCGCAAGCCAGGAAGCAGAGAGTAGCCGGA
  AGCTGACACACCTATTGAACGCAGTGACAGATGCCCTGGTCTGGGTGATTTCGAAGAGTGGAATCTCTTC
  CCAGCAGCAGTCAGTCCGTCTGGCCAACCTCCTGATGCTTCTTTCTCATGTCAGGCACATCAGTAACAAG
  GGCATGGAACATCTGCTCAGCATGAAGTGCAAAAATGTGGTCCCGGTGTACGACCTGCTGCTGGAGATGC
  TGAATGCTCACACGCTTCGAGGGTACAAGTCCTCAATCTCGGGGTCTGAGTGCTGCTCGACAGAGGACAG
  TAAGAGCAAAGAGGGCTCCCAGAACCTCCAGTCACAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR227140 representing NM_010157
  Red=Cloning site Green=Tags(s)
  
  MSICASSHKDFSQLRPTQDMEIKNSPSSLTSPASYNCSQSILPLEHGPIYIPSSYVESRHEYSAMTFYSP
  AVMNYSVPSSTGNLEGGPVRQTASPNVLWPTSGHLSPLATHCQSSLLYAEPQKSPWCEARSLEHTLPVNR
  ETLKRKLGGSGCASPVTSPSAKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQC
  TIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRIVRRQRSASEQVHCLNKAKRTSGHTPRVKELLLN
  SLSPEQLVLTLLEAEPPNVLVSRPSMPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLL
  ESCWMEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTARFRELKLQHKEYLCVK
  AMILLNSSMYPLATASQEAESSRKLTHLLNAVTDALVWVISKSGISSQQQSVRLANLLMLLSHVRHISNK
  GMEHLLSMKCKNVVPVYDLLLEMLNAHTLRGYKSSISGSECCSTEDSKSKEGSQNLQSQ
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_010157
• ORF Size: 1647 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_010157.3, NP_034287.3
• RefSeq Size: 3308
• RefSeq ORF: 1650
• Locus ID: 13983
• MW: 61.7 kDa
• Gene Summary: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation. [UniProtKB/Swiss-Prot Function]