Gdnf (NM_010275) Mouse Tagged ORF Clone
CAT#: MR227554L4
- LentiORF®
Lenti ORF clone of Gdnf (mGFP-tagged) - Mouse glial cell line derived neurotrophic factor (Gdnf)
"NM_010275" in other vectors (4)
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Product Images
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Gdnf |
Synonyms | AI385739; ATF |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR227554).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_010275 |
ORF Size | 723 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_010275.2, NP_034405.1 |
RefSeq Size | 4477 |
RefSeq ORF | 723 |
Locus ID | 14573 |
Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Homozygous knockout mice for this gene exhibit defects in kidney development and neonatal death. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC208539 | Gdnf (untagged) - Mouse glial cell line derived neurotrophic factor (Gdnf), (10ug) |
USD 540.00 |
|
MR227554 | Gdnf (Myc-DDK-tagged) - Mouse glial cell line derived neurotrophic factor (Gdnf) |
USD 420.00 |
|
MG227554 | Gdnf (GFP-tagged) - Mouse glial cell line derived neurotrophic factor (Gdnf), (10ug) |
USD 460.00 |
|
MR227554L3 | Lenti ORF clone of Gdnf (Myc-DDK-tagged) - Mouse glial cell line derived neurotrophic factor (Gdnf) |
USD 620.00 |
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