G6pc2 (NM_001289857) Mouse Tagged ORF Clone
CAT#: MR228169
- TrueORF®
G6pc2 (myc-DDK-tagged) - Mouse glucose-6-phosphatase, catalytic, 2 (G6pc2), transcript variant 3
"NM_001289857" in other vectors (1)
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Product Images
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | G6pc2 |
Synonyms | G6pc-rs; IGRP |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR228169 representing NM_001289857
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGATTTCCTTCATAGGAGTGGAGTGCTTATTATTCATCATCTGCAGGAGGACTACCGGACTTACTATG GTTTTCTAAATTTTATGTCCAATGTTGGAGACCCCCGAAATATCTTTTCTATTTACTTCCCACTTTGGTT TCAGTTGAATCAGAATGTTGGAACCAAGATGATCTGGGTAGCGGTCATAGGGGACTGGTTCAATCTCATA TTTAAATGGATATTGTTTGGCCATCGTCCTTACTGGTGGATACAAGAAACTGAGATTTATCCAAATCATT CAAGCCCATGTCTTGAGCAGTTTCCTACTACGTGTGAAACAGGCCCAGGAAGTCCATCTGGCCACGCAAT GGGCTCATCGTGCGTCTGGTATGTCATGGTAACAGCTGCCCTAAGCTACACCATCAGCCGGATGGAGGAG TCCTCTGTCACTCTGCACAGGGATGCTAGTAGCCGAGGCCTT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR228169 representing NM_001289857
Red=Cloning site Green=Tags(s) MDFLHRSGVLIIHHLQEDYRTYYGFLNFMSNVGDPRNIFSIYFPLWFQLNQNVGTKMIWVAVIGDWFNLI FKWILFGHRPYWWIQETEIYPNHSSPCLEQFPTTCETGPGSPSGHAMGSSCVWYVMVTAALSYTISRMEE SSVTLHRDASSRGL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001289857 |
ORF Size | 462 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001289857.1, NP_001276786.1 |
RefSeq Size | 1950 |
RefSeq ORF | 465 |
Locus ID | 14378 |
MW | 18.3 kDa |
Gene Summary | This gene encodes an enzyme that belongs to the glucose-6-phosphatase catalytic subunit family. Members of this family catalyze the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, to release glucose into the bloodstream. The family member encoded by this gene is found specifically in pancreatic islets but has not been shown to have phosphotransferase or phosphatase activity exhibited by a similar liver enzyme. The non-obese diabetic (NOD) mouse is a model for human type 1 diabetes, an autoimmune disease in which T lymphocytes attack and destroy insulin-producing pancreatic beta cells. In NOD mice, the protein encoded by this gene is a major target of cell-mediated autoimmunity. Variations in the human and mouse genes are associated with lower fasting plasma glucose levels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC225958 | G6pc2 (untagged) - Mouse glucose-6-phosphatase, catalytic, 2 (G6pc2), transcript variant 3 |
USD 210.00 |
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