NOC2L (NM_015658) Human Tagged ORF Clone

CAT#: RC200335

NOC2L (Myc-DDK-tagged)-Human nucleolar complex associated 2 homolog (S. cerevisiae) (NOC2L)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: NOC2L
• Synonyms: NET7; NET15; NIR; PPP1R112
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC200335 representing NM_015658
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCAGCTGCGGGGAGCCGCAAGAGGCGCCTGGCGGAGCTGACGGTGGACGAGTTCCTAGCTTCGGGCT
  TTGACTCCGAGTCCGAATCCGAGTCCGAAAATTCTCCACAAGCGGAGACACGGGAAGCACGCGAGGCTGC
  CCGGAGTCCGGATAAGCCGGGCGGGAGCCCCTCGGCCAGCCGGCGTAAAGGCCGTGCCTCTGAGCACAAA
  GACCAGCTCTCTCGGCTGAAGGACAGAGACCCCGAGTTCTACAAGTTCCTGCAGGAGAATGACCAGAGCC
  TGCTAAACTTCAGCGACTCGGACAGCTCTGAGGAGGAAGAGGGGCCGTTCCACTCCCTGCCAGATGTGCT
  GGAGGAAGCCAGTGAGGAGGAGGATGGAGCGGAGGAAGGAGAAGATGGGGACAGAGTCCCCAGAGGGCTG
  AAGGGGAAGAAGAATTCTGTTCCTGTGACCGTCGCCATGGTTGAGAGATGGAAGCAGGCAGCAAAGCAAC
  GCCTCACTCCAAAGCTGTTCCATGAAGTGGTACAGGCGTTCCGAGCAGCTGTGGCCACCACCCGAGGGGA
  CCAGGAAAGTGCTGAGGCCAACAAATTCCAGGTCACGGACAGTGCTGCATTCAATGCTCTGGTTACCTTC
  TGCATCAGAGACCTCATTGGCTGTCTCCAGAAGCTGCTGTTTGGAAAGGTGGCAAAGGATAGCAGCAGGA
  TGCTGCAGCCGTCCAGCAGCCCGCTCTGGGGGAAGCTTCGTGTGGACATCAAGGCTTACCTGGGCTCGGC
  CATACAGCTGGTGTCCTGTCTGTCGGAGACGACGGTGTTGGCGGCCGTGCTGCGGCACATCAGCGTGCTG
  GTGCCCTGCTTCCTGACCTTCCCCAAGCAGTGCCGCATGCTGCTCAAGAGAATGGTGGTCGTATGGAGCA
  CTGGGGAGGAGTCTCTGCGGGTGCTGGCTTTCCTGGTCCTCAGCAGAGTCTGCCGGCACAAGAAGGACAC
  TTTCCTTGGCCCCGTCCTCAAGCAAATGTACATCACGTATGTGAGGAACTGCAAGTTCACCTCGCCTGGT
  GCCCTCCCCTTCATCAGTTTCATGCAGTGGACCTTGACGGAGCTGCTGGCCCTGGAGCCGGGTGTGGCCT
  ACCAGCACGCCTTCCTCTACATCCGCCAGCTCGCCATACACCTGCGCAACGCCATGACCACCCGCAAGAA
  GGAAACATACCAGTCTGTGTACAACTGGCAGTATGTGCACTGCCTCTTCCTGTGGTGCCGGGTCCTGAGC
  ACTGCGGGCCCCAGCGAAGCCCTCCAGCCCTTGGTCTACCCCCTTGCCCAAGTCATCATTGGCTGTATCA
  AGCTCATCCCCACTGCCCGCTTCTACCCGCTGCGAATGCACTGCATCCGTGCCCTGACGCTGCTCTCGGG
  GAGCTCGGGGGCCTTCATCCCGGTGCTGCCTTTCATCCTGGAGATGTTCCAGCAGGTCGACTTCAACAGG
  AAGCCAGGGCGCATGAGCTCCAAGCCCATCAACTTCTCCGTGATCCTGAAGCTGTCCAATGTCAACCTGC
  AGGAGAAGGCGTACCGGGACGGCCTGGTGGAGCAGCTGTACGACCTCACCCTGGAGTACCTGCACAGCCA
  GGCACACTGCATCGGCTTCCCGGAGCTGGTGCTGCCTGTGGTCCTGCAGCTGAAGTCGTTCCTCCGGGAG
  TGCAAGGTGGCCAACTACTGCCGGCAGGTGCAGCAGCTGCTTGGGAAGGTTCAGGAGAACTCGGCATACA
  TCTGCAGCCGCCGCCAGAGGGTTTCCTTCGGCGTCTCTGAGCAGCAGGCAGTGGAAGCCTGGGAGAAGCT
  GACCCGGGAAGAGGGGACACCCTTGACCTTGTACTACAGCCACTGGCGCAAGCTGCGTGACCGGGAGATC
  CAGCTGGAGATCAGTGGCAAAGAGCGGCTGGAAGACCTGAACTTCCCTGAGATCAAACGAAGGAAGATGG
  CTGACAGGAAGGATGAGGACAGGAAGCAATTTAAAGACCTCTTTGACCTGAACAGCTCTGAAGAGGACGA
  CACCGAGGGATTCTCGGAGAGAGGGATACTGAGGCCCCTGAGCACTCGGCATGGGGTGGAAGACGATGAA
  GAGGACGAGGAGGAGGGCGAGGAGGACAGCAGCAACTCGGAGGATGGAGACCCAGACGCAGAGGCGGGGC
  TGGCCCCTGGGGAGCTGCAGCAGCTGGCCCAGGGGCCGGAGGACGAGCTGGAGGATCTGCAGCTCTCAGA
  GGACGAC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC200335 representing NM_015658
  Red=Cloning site Green=Tags(s)
  
  MAAAGSRKRRLAELTVDEFLASGFDSESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASEHK
  DQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRGL
  KGKKNSVPVTVAMVERWKQAAKQRLTPKLFHEVVQAFRAAVATTRGDQESAEANKFQVTDSAAFNALVTF
  CIRDLIGCLQKLLFGKVAKDSSRMLQPSSSPLWGKLRVDIKAYLGSAIQLVSCLSETTVLAAVLRHISVL
  VPCFLTFPKQCRMLLKRMVVVWSTGEESLRVLAFLVLSRVCRHKKDTFLGPVLKQMYITYVRNCKFTSPG
  ALPFISFMQWTLTELLALEPGVAYQHAFLYIRQLAIHLRNAMTTRKKETYQSVYNWQYVHCLFLWCRVLS
  TAGPSEALQPLVYPLAQVIIGCIKLIPTARFYPLRMHCIRALTLLSGSSGAFIPVLPFILEMFQQVDFNR
  KPGRMSSKPINFSVILKLSNVNLQEKAYRDGLVEQLYDLTLEYLHSQAHCIGFPELVLPVVLQLKSFLRE
  CKVANYCRQVQQLLGKVQENSAYICSRRQRVSFGVSEQQAVEAWEKLTREEGTPLTLYYSHWRKLRDREI
  QLEISGKERLEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDE
  EDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_015658
• ORF Size: 2247 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_015658.1, NM_015658.2, NM_015658.3, NP_056473.1
• RefSeq Size: 2762
• RefSeq ORF: 2250
• Locus ID: 26155
• Domains: UPF0120
• Protein Families: Stem cell - Pluripotency
• MW: 84.7 kDa
• Gene Summary: Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al., 2005 [PubMed 16322561]). [supplied by OMIM, Mar 2008]