BIK (NM_001197) Human Tagged ORF Clone

CAT#: RC200546L2

Lenti ORF clone of Human BCL2-interacting killer (apoptosis-inducing) (BIK), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: BIK
• Synonyms: BIP1; BP4; NBK
• Vector: pLenti-C-mGFP
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200546).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_001197
• ORF Size: 480 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001197.3, NP_001188.1
• RefSeq Size: 966
• RefSeq ORF: 483
• Locus ID: 638
• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transmembrane
• MW: 18 kDa
• Gene Summary: The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011]