C3IP1 (KLHL12) (NM_021633) Human Tagged ORF Clone
CAT#: RC200894L4
- LentiORF®
Lenti ORF clone of Human kelch-like 12 (Drosophila) (KLHL12), mGFP tagged
"NM_021633" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | KLHL12 |
Synonyms | C3IP1; DKIR |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC200894).
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Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_021633 |
ORF Size | 1704 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_021633.2, NP_067646.1 |
RefSeq Size | 3338 |
RefSeq ORF | 1707 |
Locus ID | 59349 |
Domains | BTB, Kelch |
MW | 63.3 kDa |
Gene Summary | This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
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SC112907 | KLHL12 (untagged)-Human kelch-like 12 (Drosophila) (KLHL12) |
USD 310.00 |
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RC200894 | KLHL12 (Myc-DDK-tagged)-Human kelch-like 12 (Drosophila) (KLHL12) |
USD 420.00 |
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RG200894 | KLHL12 (GFP-tagged) - Human kelch-like 12 (Drosophila) (KLHL12) |
USD 460.00 |
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RC200894L1 | Lenti ORF clone of Human kelch-like 12 (Drosophila) (KLHL12), Myc-DDK-tagged |
USD 768.00 |
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RC200894L2 | Lenti ORF clone of Human kelch-like 12 (Drosophila) (KLHL12), mGFP tagged |
USD 620.00 |
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RC200894L3 | Lenti ORF clone of Human kelch-like 12 (Drosophila) (KLHL12), Myc-DDK-tagged |
USD 620.00 |
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