Hsp22 (HSPB8) (NM_014365) Human Tagged ORF Clone
CAT#: RC201040L4
- LentiORF®
Lenti ORF clone of Human heat shock 22kDa protein 8 (HSPB8), mGFP tagged
"NM_014365" in other vectors (6)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | HSPB8 |
Synonyms | CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC201040).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_014365 |
ORF Size | 588 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_014365.2, NP_055180.1 |
RefSeq Size | 2056 |
RefSeq ORF | 591 |
Locus ID | 26353 |
Domains | HSP20 |
Protein Families | Druggable Genome, Protein Kinase |
MW | 21.6 kDa |
Gene Summary | The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC115063 | HSPB8 (untagged)-Human heat shock 22kDa protein 8 (HSPB8) |
USD 310.00 |
|
RC201040 | HSPB8 (Myc-DDK-tagged)-Human heat shock 22kDa protein 8 (HSPB8) |
USD 98.00 |
|
RG201040 | HSPB8 (GFP-tagged) - Human heat shock 22kDa protein 8 (HSPB8) |
USD 460.00 |
|
RC201040L1 | Lenti ORF clone of Human heat shock 22kDa protein 8 (HSPB8), Myc-DDK-tagged |
USD 768.00 |
|
RC201040L2 | Lenti ORF clone of Human heat shock 22kDa protein 8 (HSPB8), mGFP tagged |
USD 768.00 |
|
RC201040L3 | Lenti ORF clone of Human heat shock 22kDa protein 8 (HSPB8), Myc-DDK-tagged |
USD 768.00 |
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