UBA2 (NM_005499) Human Tagged ORF Clone

CAT#: RC201288L4

Lenti ORF clone of Human ubiquitin-like modifier activating enzyme 2 (UBA2), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: UBA2
• Synonyms: ARX; HRIHFB2115; SAE2
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201288).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_005499
• ORF Size: 1920 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005499.2, NP_005490.1
• RefSeq Size: 2682
• RefSeq ORF: 1923
• Locus ID: 10054
• Domains: UBACT, ThiF
• Protein Pathways: Ubiquitin mediated proteolysis
• MW: 71 kDa
• Gene Summary: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]). [supplied by OMIM, Mar 2010]