UBA2 (NM_005499) Human Untagged Clone

CAT#: SC319458

UBA2 (untagged)-Human ubiquitin-like modifier activating enzyme 2 (UBA2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBA2
• Synonyms: ARX; HRIHFB2115; SAE2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005499.2 CTCGGTTCTCCCGCCTCCGCCTCCGCCGCGGCTCGTGGTTGTCCCGCCATGGCACTGTCG
  CGGGGGCTGCCCCGGGAGCTGGCTGAGGCGGTGGCCGGGGGCCGGGTGCTGGTGGTGGGG
  GCGGGCGGCATCGGCTGCGAGCTCCTCAAGAATCTCGTGCTCACCGGTTTCTCCCACATC
  GACCTGATTGATCTGGATACTATTGATGTAAGCAACCTCAACAGACAGTTTTTGTTTCAA
  AAGAAACATGTTGGAAGATCAAAGGCACAGGTTGCCAAGGAAAGTGTACTGCAGTTTTAC
  CCGAAAGCTAATATCGTTGCCTACCATGACAGCATCATGAACCCTGACTATAATGTGGAA
  TTTTTCCGACAGTTTATACTGGTTATGAATGCTTTAGATAACAGAGCTGCCCGAAACCAT
  GTTAATAGAATGTGCCTGGCAGCTGATGTTCCTCTTATTGAAAGTGGAACAGCTGGGTAT
  CTTGGACAAGTAACTACTATCAAAAAGGGTGTGACCGAGTGTTATGAGTGTCATCCTAAG
  CCGACCCAGAGAACCTTTCCTGGCTGTACAATTCGTAACACACCTTCAGAACCTATACAT
  TGCATCGTTTGGGCAAAGTACTTGTTCAACCAGTTGTTTGGGGAAGAAGATGCTGATCAA
  GAAGTATCTCCTGACAGAGCTGACCCTGAAGCTGCCTGGGAACCAACGGAAGCCGAAGCC
  AGAGCTAGAGCATCTAATGAAGATGGTGACATTAAACGTATTTCTACTAAGGAATGGGCT
  AAATCAACTGGATATGATCCAGTTAAACTTTTTACCAAGCTTTTTAAAGATGACATCAGG
  TATCTGTTGACAATGGACAAACTATGGCGGAAAAGGAAACCTCCAGTTCCGTTGGACTGG
  GCTGAAGTACAAAGTCAAGGAGAAGAAACGAATGCATCAGATCAACAGAATGAACCCCAG
  TTAGGCCTGAAAGACCAGCAGGTTCTAGATGTAAAGAGCTATGCACGTCTTTTTTCAAAG
  AGCATCGAGACTTTGAGAGTTCATTTAGCAGAAAAGGGGGATGGAGCTGAGCTCATATGG
  GATAAGGATGACCCATCTGCAATGGATTTTGTCACCTCTGCTGCAAACCTCAGGATGCAT
  ATTTTCAGTATGAATATGAAGAGTAGATTTGATATCAAATCAATGGCAGGGAACATTATT
  CCTGCTATTGCTACTACTAATGCAGTAATTGCTGGGTTGATAGTATTGGAAGGATTGAAG
  ATTTTATCAGGAAAAATAGACCAGTGCAGAACAATTTTTTTGAATAAACAACCAAACCCA
  AGAAAGAAGCTTCTTGTGCCTTGTGCACTGGATCCTCCCAACCCCAATTGTTATGTATGT
  GCCAGCAAGCCAGAGGTGACTGTGCGGCTGAATGTCCATAAAGTGACTGTTCTCACCTTA
  CAAGACAAGATAGTGAAAGAAAAATTTGCTATGGTAGCACCAGATGTCCAAATTGAAGAT
  GGGAAAGGAACAATCCTAATATCTTCCGAAGAGGGAGAGACGGAAGCTAATAATCACAAG
  AAGTTGTCAGAATTTGGAATTAGAAATGGCAGCCGGCTTCAAGCAGATGACTTCCTCCAG
  GACTATACTTTATTGATCAACATCCTTCATAGTGAAGACCTAGGAAAGGACGTTGAATTT
  GAAGTTGTTGGTGATGCCCCGGAAAAAGTGGGGCCCAAACAAGCTGAAGATGCTGCCAAA
  AGCATAACCAATGGCAGTGATGATGGAGCTCAGCCCTCCACCTCCACAGCTCAAGAGCAA
  GATGACGTTCTCATAGTTGATTCGGATGAAGAAGATTCTTCAAATAATGCCGACGTCAGT
  GAAGAAGAGAGAAGCCGCAAGAGGAAATTAGATGAGAAAGAGAATCTCAGTGCAAAGAGG
  TCACGTATAGAACAGAAGGAAGAGCTTGATGATGTCATAGCATTAGATTGAACAGAAATG
  CCTCTAAACAGAACCCTCTTACTATTTAGTTTATCTGGGCAGAACCAGATTGTTATGTCC
  TTTGTTCCAAAGGGAAAAAATTGACAGCAGTGACTTGAAAATGATTCTGCTCCCTTTGAA
  AGCATTCATTTTGCTAGAACTGTTAGACACATTGCAGTATGCTGTATTGAAAGTAGGAAT
  ATAGTTTTAAAAACCCTTTGAACAAAGTGTGTGCATAACCAGTCATGAGATAAAACAACA
  CAATGCATGTTGCCTTTTTAATGTAAATACCCTTAGGTATCATTAATAGTTTCAAAATAT
  TGTGGTTTAGTAAAGTTGATACCTGGTTATAAATATTATGCCTTTATTTTTGGCTAGAAG
  AAGAATTATTTTTAGCCTAGATCTAACCATTTTCATACTCTTAACTGATTGAAACAGATT
  CAAAGAAGTATCGAGTGCTATGCATTGAAACTTGTTTTTAAATGTTAGATGGCACTATGT
  ATATTAATGTAAAACAATGTTAATTTACTCAAGTTTTCAGTTTGTACCGCCTGGTATGTC
  TGTGTAAGAAGCCAATTTTTGTGTATTGTTACAGTTTCAGGTTATTTATATTCGATGTTT
  TGTAAAACTCAAATAACGACTATACTTATGGACCAAATAAATGGCATCTGCATTCTTGTT
  AAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005499.2 unedited
  GACCATTTGTCATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGCTCGGTTCTC
  CCGCCTCCGCTCTCCGCCGCGGCTCGTGGTTGTCCCGCCATGGCACTGTCGCGGGGGCTG
  CCCCGGGAGCTGGCTGAGGCGGTGGCCGGGGGCCGGGTGCTGGTGGTGGGGGCGGGCGGC
  ATCGGCTGCGAGCTCCTCAAGAATCTCGTGCTCACCGGTTTCTCCCACATCGACCTGATT
  GATCTGGATACTATTGATGTAAGCAACCTCAACAGACAGTTTTTGTTTCAAAAGAAACAT
  GTTGGAAGATCAAAGGCACAGGTTGCCATGTTAAAGTGGACTGCAGTTTTACCCGAAAGC
  TAATATCGTTGCCTACCATGACAGCATCATGAACCCTGACTATAATGTGGAATTTTTCCG
  ACAGTTTATACTGGTTATGAATGCTTTAGATAACAGAGCTGCCCGAAACCATGTTAATAG
  AATGTGCCTGGCAGCTGATGTTCCTCTTATTGAAAGTGGAACAGCTGGGTATCTTGGACA
  AGTAACTACTATCAAAAAGGGTGTGACCGAGTGTTATGAGTGTCATCCTAAGCCGACCCA
  GAGAACCTTTCCTGGCTGTACAATTCGTAACACACCTTCAGAACCTATACATTGCATCGT
  TTGGGCAAAGTACTTGTTCAACCAGTTGTTTGGGGAAGAGATGCTGATCAAGAAGTATCT
  CCTGACAGAGCTGACCCTGAAGCTGCCTGGGAACCAACGAGCCGAGCCAGAGCTAGAGCA
  TCTATGAGATGGTGACATTAAACGTATTTTCTACTAAGATGGGCTAAATCAACTGAGTAT
  GATCCAGTTAAACTTTTACCAGCTTTTAAGATGAACATCAGTATTCTGTTGACAATGGAC
  AAACATATGGCGGAAAAGAGAAACTTC
• Restriction Sites: Please inquire
• ACCN: NM_005499
• ORF Size: 1923 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005499.2, NP_005490.1
• RefSeq Size: 2682
• RefSeq ORF: 1923
• Locus ID: 10054
• Domains: UBACT, ThiF
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]). [supplied by OMIM, Mar 2010]