HMG20A (NM_018200) Human Tagged ORF Clone

CAT#: RC201894L4

Lenti ORF clone of Human high mobility group 20A (HMG20A), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: HMG20A
• Synonyms: HMGX1; HMGXB1
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201894).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_018200
• ORF Size: 1041 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_018200.2, NP_060670.1
• RefSeq Size: 3898
• RefSeq ORF: 1044
• Locus ID: 10363
• Domains: HMG
• Protein Families: Transcription Factors
• MW: 40.1 kDa
• Gene Summary: Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4. [UniProtKB/Swiss-Prot Function]