KLHL9 (NM_018847) Human Tagged ORF Clone

CAT#: RC203728L4

Lenti-ORF clone of KLHL9 (mGFP-tagged)-Human kelch-like 9 (Drosophila) (KLHL9)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: KLHL9
• Synonyms: RP11-380P16.6
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203728).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_018847
• ORF Size: 1851 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_018847.2, NP_061335.1
• RefSeq Size: 4412
• RefSeq ORF: 1854
• Locus ID: 55958
• Domains: BTB, Kelch
• Protein Pathways: Ubiquitin mediated proteolysis
• MW: 69.2 kDa
• Gene Summary: This gene encodes a protein that belongs to the kelch repeat-containing family, and contains an N-terminal BTB/POZ domain, a BACK domain and six C-terminal kelch repeats. The encoded protein is a component of a complex with cullin 3-based E3 ligase, which plays a role in mitosis. This protein complex is a cell cycle regulator, and functions in the organization and integrity of the spindle midzone in anaphase and the completion of cytokinesis. The complex is required for the removal of the chromosomal passenger protein aurora B from mitotic chromosomes. [provided by RefSeq, Jul 2016]