ADH5 (NM_000671) Human Tagged ORF Clone
CAT#: RC204903L2
- LentiORF®
Lenti ORF clone of Human alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5), mGFP tagged
"NM_000671" in other vectors (7)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | ADH5 |
Synonyms | ADH-3; ADHX; FALDH; FDH; GSH-FDH; GSNOR; HEL-S-60p |
Vector | pLenti-C-mGFP |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC204903).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_000671 |
ORF Size | 1122 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000671.3, NP_000662.3 |
RefSeq Size | 2652 bp |
RefSeq ORF | 1125 bp |
Locus ID | 128 |
Cytogenetics | 4q23 |
Domains | ADH_zinc_N |
Protein Families | Druggable Genome |
Protein Pathways | Drug metabolism - cytochrome P450, Fatty acid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Methane metabolism, Retinol metabolism, Tyrosine metabolism |
MW | 39.7 kDa |
Gene Summary | 'This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
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SC119755 | ADH5 (untagged)-Human alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5) |
USD 310.00 |
|
SC320918 | ADH5 (untagged)-Human alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5) |
USD 310.00 |
|
RC204903 | ADH5 (Myc-DDK-tagged)-Human alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5) |
USD 98.00 |
|
RG204903 | ADH5 (GFP-tagged) - Human alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5) |
USD 460.00 |
|
RC204903L1 | Lenti ORF clone of Human alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5), Myc-DDK-tagged |
USD 768.00 |
|
RC204903L3 | Lenti ORF clone of Human alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5), Myc-DDK-tagged |
USD 620.00 |
|
RC204903L4 | Lenti ORF clone of Human alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5), mGFP tagged |
USD 620.00 |
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