CD8A (NM_001768) Human Tagged ORF Clone
CAT#: RC206608L4
- LentiORF®
Lenti ORF clone of Human CD8a molecule (CD8A), transcript variant 1, mGFP tagged
"NM_001768" in other vectors (7)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | CD8A |
Synonyms | CD8; Leu2; p32 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC206608).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_001768 |
ORF Size | 705 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001768.5, NP_001759.3 |
RefSeq Size | 3035 bp |
RefSeq ORF | 708 bp |
Locus ID | 925 |
Cytogenetics | 2p11.2 |
Domains | ig, IGv, IG |
Protein Families | Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane |
Protein Pathways | Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway |
MW | 25.7 kDa |
Gene Summary | 'The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC111602 | CD8A (untagged)-Human CD8a molecule (CD8A), transcript variant 1 |
USD 310.00 |
|
SC322577 | CD8A (untagged)-Human CD8a molecule (CD8A), transcript variant 1 |
USD 420.00 |
|
RC206608 | CD8A (Myc-DDK-tagged)-Human CD8a molecule (CD8A), transcript variant 1 |
USD 98.00 |
|
RG206608 | CD8A (GFP-tagged) - Human CD8a molecule (CD8A), transcript variant 1 |
USD 460.00 |
|
RC206608L1 | Lenti ORF clone of Human CD8a molecule (CD8A), transcript variant 1, Myc-DDK-tagged |
USD 768.00 |
|
RC206608L2 | Lenti ORF clone of Human CD8a molecule (CD8A), transcript variant 1, mGFP tagged |
USD 620.00 |
|
RC206608L3 | Lenti ORF clone of Human CD8a molecule (CD8A), transcript variant 1, Myc-DDK-tagged |
USD 620.00 |
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