ARH (LDLRAP1) (NM_015627) Human Tagged ORF Clone

CAT#: RC206643L4

Lenti ORF clone of Human low density lipoprotein receptor adaptor protein 1 (LDLRAP1), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: LDLRAP1
• Synonyms: ARH; ARH1; ARH2; FHCB1; FHCB2
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206643).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_015627
• ORF Size: 924 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_015627.1, NP_056442.1
• RefSeq Size: 2862
• RefSeq ORF: 927
• Locus ID: 26119
• Domains: PID
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis
• MW: 33.7 kDa
• Gene Summary: The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia. [provided by RefSeq, Jul 2008]