PLA2G3 (NM_015715) Human Tagged ORF Clone
CAT#: RC206872L3
- LentiORF®
Lenti ORF clone of Human phospholipase A2, group III (PLA2G3), Myc-DDK-tagged
"NM_015715" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | PLA2G3 |
Synonyms | GIII-SPLA2; sPLA2-III; SPLA2III |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC206872).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_015715 |
ORF Size | 1527 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_015715.2, NP_056530.1 |
RefSeq Size | 2717 |
RefSeq ORF | 1530 |
Locus ID | 50487 |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway |
MW | 57.2 kDa |
Gene Summary | This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease. [provided by RefSeq, Apr 2014] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC122829 | PLA2G3 (untagged)-Human phospholipase A2, group III (PLA2G3) |
USD 310.00 |
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RC206872 | PLA2G3 (Myc-DDK-tagged)-Human phospholipase A2, group III (PLA2G3) |
USD 480.00 |
|
RG206872 | PLA2G3 (GFP-tagged) - Human phospholipase A2, group III (PLA2G3) |
USD 530.00 |
|
RC206872L1 | Lenti ORF clone of Human phospholipase A2, group III (PLA2G3), Myc-DDK-tagged |
USD 680.00 |
|
RC206872L2 | Lenti ORF clone of Human phospholipase A2, group III (PLA2G3), mGFP tagged |
USD 680.00 |
|
RC206872L4 | Lenti ORF clone of Human phospholipase A2, group III (PLA2G3), mGFP tagged |
USD 840.00 |
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