PLA2G3 (NM_015715) Human Untagged Clone

CAT#: SC122829

PLA2G3 (untagged)-Human phospholipase A2, group III (PLA2G3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PLA2G3
• Synonyms: GIII-SPLA2; sPLA2-III; SPLA2III
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_015715 edited
  CATTCATTGGTCCCGCCGCACCGGGCCTGCTGGGCTCCGCTTCCGTTCCACTGCTCAGCT
  GCCGCCTGGTGGGGCCACCAAGGGCAGGCATCCCAGGGGCTTTGTCTGACTGGACTGGGC
  CAGTGCAGAATGGGGGTTCAGGCAGGGCTGTTTGGGATGCTGGGCTTCCTGGGGGTGGCC
  CTGGGGGGCTCCCCTGCCCTCCGCTGGTACAGGACCTCCTGCCACTTGACCAAGGCCGTC
  CCTGGCAACCCACTGGGGTACCTGAGCTTCCTGGCCAAGGATGCTCAGGGACTGGCCCTG
  ATCCATGCCCGCTGGGATGCGCATAGGAGGCTGCAGGCATGTAGCTGGGAGGATGAGCCG
  GAGCTCACCGCAGCCTACGGTGCTCTCTGTGCTCATGAGACTGCCTGGGGCTCCTTCATC
  CACACCCCCGGACCCGAGCTGCAGAGAGCACTGGCCACTCTTCAGAGTCAGTGGGAGGCA
  TGCCGAGCGCTTGAGGAGAGTCCAGCAGGGGCCAGGAAGAAGCGAGCAGCAGGGCAGAGT
  GGAGTCCCTGGTGGAGGGCACCAGCGAGAGAAGAGAGGATGGACCATGCCTGGCACACTG
  TGGTGTGGAGTTGGAGATTCTGCTGGGAACTCCTCGGAGCTGGGGGTCTTCCAGGGACCT
  GATCTCTGTTGCCGGGAACATGACCGCTGCCCACAGAACATCTCACCCTTGCAGTACAAC
  TATGGCATCCGAAACTACCGATTCCACACCATCTCCCACTGTGACTGTGACACCAGGTTT
  CAGCAATGCCTACAGAATCAGCACGACTCCATCTCGGACATCGTGGGCGTGGCCTTCTTC
  AACGTGCTGGAGATCCCCTGCTTTGTGCTGGAGGAGCAGGAGGCGTGTGTGGCGTGGTAC
  TGGTGGGGCGGGTGTAGGATGTATGGCACAGTGCCCCTCGCTCGCCTGCAGCCCAGGACC
  TTCTACAATGCCTCCTGGAGCTCCCGGGCCACCTCCCCAACTCCCAGCTCCCGGAGCCCA
  GCCCCTCCCAAGCCTCGACAGAAGCAGCACCTTCGGAAGGGGCCACCACATCAGAAAGGG
  TCCAAGCGCCCCAGCAAAGCCAACACCACAGCCCTCCAGGACCCTATGGTCTCTCCCAGG
  CTTGATGTGGCCCCCACAGGCCTCCAGGGCCCACAGGGTGGCCTAAAACCTCAGGGTGCC
  CGCTGGGTCTGCCGCAGCTTCCGCCGCCACCTGGACCAGTGTGAGCACCAGATTGGGCCC
  CGGGAAATCGAGTTCCAGCTGCTCAACAGCGCCCAAGAGCCCCTCTTCCACTGCAACTGC
  ACGCGCCGTCTGGCACGCTTCCTGAGGCTCCACAGCCCACCCGAGGTTACCAACATGCTT
  TGGGAGCTGCTGGGCACAACCTGCTTCAAGCTGGCCCCTCCACTGGACTGTGTGGAAGGC
  AAAAACTGTTCCAGAGACCCTAGGGCCATCAGGGTGTCAGCCCGGCACTTGCGGAGGCTT
  CAGCAGAGGCGACACCAGCTCCAGGATAAAGGCACAGATGAGAGGCAGCCATGGCCTTCA
  GAGCCCCTGAGAGGCCCCATGTCATTCTACAACCAGTGCCTGCAGCTAACCCAGGCAGCC
  AGGAGACCCGACAGGCAGCAGAAGTCCTGGAGCCAGTGACCTCAGTTTCAGCTTTCCTGG
  GCACCAGCCTGGACCTTGCCCATGGCTATGCCAAGCCTTGGGAATCTCAGCCTCCCCTCC
  GTAGGTTAGACTGAAGCATGGCAGAGGCTGTTGTGGACAATCAAGAGGATGAATGGGGGG
  ATCTCAAGGCCCAAATGCTGGACCACATCTCCTGCTGTTCTGGGTAACCTTGAGCTATGT
  ATGACACAACTCTTCTATGCCTGGATGTGGTGTTCAGGAAGCTCATTCTGATGCCCTGGG
  CTTTGGCCTTGCCAGGGAACTTCACATACAGATGAGAATGGGGAAAGGGTAACTTATTGC
  AGCAGCCCCAGGCAGTACCAGGAGGAGGTACATGTATGTCCGTGTTGCAAAAATAATACA
  TGCCTCAAAAACCTGCCTAGGGGAGCCCTAGTGCCTGGGTGCTGTGGCCTGAGGTAGCAG
  GTGGGAAGTTAGGGATGTCACAGAAATGTCTGTGTCTGAATCCAGGATTGGGGTGGGTGT
  TGGAGAGGGCTTTCAGCTCCCCTCCTCCCAGGGGGGCCTCTTTTTTTAACGGCTGCCGTG
  CCCTTCCTGGCCCATCCCTAAACCTAAATTCAAATCTCCTCCATGCCTTTGCGCAAAGGA
  CCTCCCTCTTGCACTCTAAGCCTTAGTTTCCTCCTCTAAAAAAAGGGGGTCTCTAAACAG
  GAGCTACCTCATAGGGTTGTTGAGGATTAAGTGAACCAATACATATACAGTGCTTAGCAC
  TTAATAAGTACTCCCCCCTGCGACACCTAGCTGAACTATGGTTTGGTGTCTGATCTTGAG
  AGGTTGATGTAACCTTTTAAAGGCCTCAGTTCGCTCACCTGTGAAATGGGTCTAAGAATA
  GCACTGATCTCACAGGGTTGTGATGCAGATTAAAGGAGATGGCATGTGTAATGTAAAAAA
  AAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015715 unedited
  AGAGTTCAAATATTTNGTATACGACTCACTATAGGGCGGCNCGCGAATTCGCACGAGGCA
  TTCATTGGTCCCGCCGCACCGGGCCTGCTGGGCTCCGCTTCCGTTCCACTGCTCAGCTGC
  CGCCTGGTGGGGCCACCAAGGGCAGGCATCCCAGGGGCTTTGTCTGACTGGACTGGGCCA
  GTGCAGAATGGGGGTTCAGGCAGGGCTGTTTGGGATGCTGGGCTTCCTGGGGGTGGCCCT
  GGGGGGCTCCCCTGCCCTCCGCTGGTACAGGACCTCCTGCCACTTGACCAAGGCCGTCCC
  TGGCAACCCACTGGGGTACCTGAGCTTCCTGGCCAAGGATGCTCAGGGACTGGCCCTGAT
  CCATGCCCGCTGGGATGCGCATAGGAGGCTGCAGGCATGTAGCTGGGAGGATGAGCCGGA
  GCTCACCGCAGCCTACGGTGCTCTCTGTGCTCATGAGACTGCCTGGGGCTCCTTCATCCA
  CACCCCCGGACCCGAGCTGCAGAGAGCACTGGCCACTCTTCAGAGTCAGTGGGAGGCATG
  CCGAGCGCTTGAGGAGAGTCCAGCAGGGGCCAGGAAGAAGCGAGCAGCAGGGCAGAGTGG
  AGTCCCTGGTGGAGGGCACCAGCGAGAGAAGAGAGGATGGACCATGCCTGGCACACTGTG
  GTGTGGAGTTGGAGATTCTGCTGGGAACTCCTCGGAGCTGGGGGTCTTCCAGGGACCTGA
  TCTCTGTTGCCGGGAACATGACCGCTGCCCACAAACATCTCACCCTTGCAGTACAACTAT
  GGGAATCCAAAACTACCGATTCCACAACATCTCCCACTGTGACTGTGACACCCGTTTTCA
  ACCATGGCTAAAGAATCAGCACGAATTCATCTTGGACATGTGGGCGTGGGCCTCTTCACG
  TGCTGGAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_015715
• ORF Size: 1530 bp
• Insert Size: 2593
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_015715.2, NP_056530.1
• RefSeq Size: 2593
• RefSeq ORF: 1530
• Locus ID: 50487
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway
• Gene Summary: This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease. [provided by RefSeq, Apr 2014]