TIRAP (NM_001039661) Human Tagged ORF Clone
CAT#: RC207162L3
- LentiORF®
Lenti ORF clone of Human toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), transcript variant 3, Myc-DDK-tagged
"NM_001039661" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | TIRAP |
Synonyms | BACTS1; Mal; MyD88-2; wyatt |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC207162).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_001039661 |
ORF Size | 666 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001039661.1 |
RefSeq Size | 2348 |
RefSeq ORF | 666 |
Locus ID | 114609 |
Protein Families | Druggable Genome |
Protein Pathways | Toll-like receptor signaling pathway |
MW | 28 kDa |
Gene Summary | The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC324197 | TIRAP (untagged)-Human toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), transcript variant 3 |
USD 420.00 |
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RC207162 | TIRAP (Myc-DDK-tagged)-Human toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), transcript variant 3 |
USD 98.00 |
|
RG207162 | TIRAP (GFP-tagged) - Human toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), transcript variant 3 |
USD 460.00 |
|
RC207162L1 | Lenti ORF clone of Human toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), transcript variant 3, Myc-DDK-tagged |
USD 768.00 |
|
RC207162L2 | Lenti ORF clone of Human toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), transcript variant 3, mGFP tagged |
USD 620.00 |
|
RC207162L4 | Lenti ORF clone of Human toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), transcript variant 3, mGFP tagged |
USD 620.00 |
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