SEM1 (NM_006304) Human Tagged ORF Clone

CAT#: RC207564L4

Lenti ORF clone of Human split hand/foot malformation (ectrodactyly) type 1 (SHFM1), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: SEM1
• Synonyms: C7orf76; DSS1; ECD; SHFD1; Shfdg1; SHFM1; SHSF1
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207564).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_006304
• ORF Size: 210 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006304.1, NP_006295.1
• RefSeq Size: 509
• RefSeq ORF: 213
• Locus ID: 7979
• Domains: DSS1_SEM1
• Protein Pathways: Homologous recombination, Proteasome
• MW: 8.3 kDa
• Gene Summary: The product of this gene has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle. [provided by RefSeq, Jul 2008]