PDXP (NM_020315) Human Tagged ORF Clone

CAT#: RC209456L3

Lenti-ORF clone of PDXP (Myc-DDK-tagged)-Human pyridoxal (pyridoxine, vitamin B6) phosphatase (PDXP)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: PDXP
• Synonyms: CIN; dJ37E16.5; PLP
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209456).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_020315
• ORF Size: 888 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_020315.4, NP_064711.1
• RefSeq Size: 2072
• RefSeq ORF: 891
• Locus ID: 57026
• Domains: Hydrolase
• Protein Pathways: Metabolic pathways, Vitamin B6 metabolism
• MW: 31.5 kDa
• Gene Summary: Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al., 2003 [PubMed 14522954]). [supplied by OMIM, Mar 2008]