EBP1 (PA2G4) (NM_006191) Human Tagged ORF Clone

CAT#: RC210230L2

Lenti ORF clone of Human proliferation-associated 2G4, 38kDa (PA2G4), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: PA2G4
• Synonyms: EBP1; HG4-1; p38-2G4
• Vector: pLenti-C-mGFP
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210230).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_006191
• ORF Size: 1182 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006191.2, NP_006182.1, NP_006182.2
• RefSeq Size: 2643
• RefSeq ORF: 1185
• Locus ID: 5036
• Domains: Peptidase_M24
• Protein Families: Druggable Genome, Protease, Stem cell - Pluripotency
• MW: 43.6 kDa
• Gene Summary: This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq, Jul 2008]