SF3B4 (NM_005850) Human Tagged ORF Clone

CAT#: RC210352L3

Lenti-ORF clone of SF3B4 (Myc-DDK-tagged)-Human splicing factor 3b, subunit 4, 49kDa (SF3B4)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: SF3B4
• Synonyms: AFD1; Hsh49; SAP49; SF3b49
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210352).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_005850
• ORF Size: 1272 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005850.4, NP_005841.1
• RefSeq Size: 2001
• RefSeq ORF: 1275
• Locus ID: 10262
• Domains: RRM
• Protein Pathways: Spliceosome
• MW: 44.4 kDa
• Gene Summary: This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq, Jul 2008]