PLA2G12B (NM_032562) Human Tagged ORF Clone
CAT#: RC210905L2
- LentiORF®
Lenti ORF clone of Human phospholipase A2, group XIIB (PLA2G12B), mGFP tagged
"NM_032562" in other vectors (6)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | PLA2G12B |
Synonyms | FKSG71; GXIIB; GXIIIsPLA2; PLA2G13; sPLA2-GXIIB |
Vector | pLenti-C-mGFP |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC210905).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_032562 |
ORF Size | 585 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_032562.2, NP_115951.2 |
RefSeq Size | 1092 |
RefSeq ORF | 588 |
Locus ID | 84647 |
Protein Families | Secreted Protein |
Protein Pathways | alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway |
MW | 21.7 kDa |
Gene Summary | The protein encoded by this gene belongs to the phospholipase A2 (PLA2) group of enzymes, which function in glycolipid hydrolysis with the release of free fatty acids and lysophospholipids. This family member has altered phospholipid-binding properties and is catalytically inactive. The protein is secreted, and together with microsomal triglyceride transfer protein, it functions to regulate HNF4alpha-induced hepatitis C virus infectivity. The expression of this gene is down-regulated in various tumors, suggesting that it may function as a negative regulator of tumor progression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC305474 | PLA2G12B (untagged)-Human phospholipase A2, group XIIB (PLA2G12B) |
USD 420.00 |
|
RC210905 | PLA2G12B (Myc-DDK-tagged)-Human phospholipase A2, group XIIB (PLA2G12B) |
USD 98.00 |
|
RG210905 | PLA2G12B (GFP-tagged) - Human phospholipase A2, group XIIB (PLA2G12B) |
USD 460.00 |
|
RC210905L1 | Lenti ORF clone of Human phospholipase A2, group XIIB (PLA2G12B), Myc-DDK-tagged |
USD 768.00 |
|
RC210905L3 | Lenti ORF clone of Human phospholipase A2, group XIIB (PLA2G12B), Myc-DDK-tagged |
USD 620.00 |
|
RC210905L4 | Lenti ORF clone of Human phospholipase A2, group XIIB (PLA2G12B), mGFP tagged |
USD 620.00 |
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